乌替普利
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- CAS号:
- 109683-61-6
- 英文名:
- Utibapril
- 英文别名:
- Utibapril;FPL-63547;(2S)-5-tert-Butyl-3-[(2S)-2-[[(1S)-1-ethoxycarbonyl-3-phenylpropyl]amino]propanoyl]-2,3-dihydro-1,3,4-thiadiazole-2β-carboxylic acid;1,3,4-Thiadiazole-2-carboxylic acid, 5-(1,1-dimethylethyl)-3-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-2,3-dihydro-, (2S)-
- 中文名:
- 乌替普利
- 中文别名:
- 乌替普利;化合物 T13274
- CBNumber:
- CB21116205
- 分子式:
- C22H31N3O5S
- 分子量:
- 449.569
- MOL File:
- 109683-61-6.mol
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乌替普利化学性质
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储存条件:
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Store at -20°C
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溶解度:
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Soluble in DMSO
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乌替普利性质、用途与生产工艺
Utibapril 是一种 angiotensin-converting enzyme (ACE) 抑制剂，具有抗高血压的功效。
Utibapril significantly inhibits plasma, renal, and vascular ACE but not ventricular ACE activity. Utibapril (2 μg/kg/day) significantly inhibits vascular ACE activity, and Utibapril (250 μg/kg/day) results in a significant inhibition of plasma ACE. Furthermore, angiotensin I-induced decreases in coronary flow in the isolated heart are significantly inhibited after treatment with the higher doses of utibapril. FPL 63547 is rapidly and extensively excreted as the diacid in the bile but appeared in the urine in negligible amounts.
乌替普利
上下游产品信息
上游原料
下游产品
109683-61-6, 乌替普利 相关搜索:
- C22H31N3O5S
- 化合物 T13274
- 乌替普利
- 109683-61-6
- 1,3,4-Thiadiazole-2-carboxylic acid, 5-(1,1-dimethylethyl)-3-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-2,3-dihydro-, (2S)-
- Utibapril
- FPL-63547
- (2S)-5-tert-Butyl-3-[(2S)-2-[[(1S)-1-ethoxycarbonyl-3-phenylpropyl]amino]propanoyl]-2,3-dihydro-1,3,4-thiadiazole-2β-carboxylic acid