MDK-7933
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- CAS号:
- 1417997-93-3
- 英文名:
- (E)-N-hydroxy-4-methoxy-2-(biphenyl-4-yl)cinnamamide
- 英文别名:
- 22d;HDAC8-IN-1;CS-2693;MDK-7933;INVIVO-7933;HDAC8-IN-22d;HDAC8-IN-1(22d);HDAC8 inhibitor 1;HDAC8 inhibitor 22d;HDAC8-IN-1 ,MDK7933
- 中文名:
- MDK-7933
- 中文别名:
- 化合物HDAC8-IN-1;(E)-N-羟基-3-(5-甲氧基-[1,1':4',1''-三联苯]-2-基)丙烯酰胺;(E)-N-羟基-3-(5-甲氧基-[1,1':4',1''-三联苯]-2-基)丙烯酰胺
- CBNumber:
- CB23373154
- 分子式:
- C22H19NO3
- 分子量:
- 345.39
- MOL File:
- 1417997-93-3.mol
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MDK-7933化学性质
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密度:
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1?+-.0.06 g/cm3(Predicted)
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储存条件:
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Store at -20°C
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溶解度:
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DMSO: soluble
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形态:
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A solid
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酸度系数(pKa):
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8.76±0.23(Predicted)
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MDK-7933性质、用途与生产工艺
HDAC8-IN-1 是一个 HDAC8 抑制剂，其 IC50 值为 27.2 nM。
HDAC8-IN-1 is a HDAC8 inhibitor with an IC
50
of 27.2 nM in cancer cell lines. HDAC8-IN-1 (compound 22 d) shows antiproliferative effects toward several human lung cancer cell lines (A549, H1299, and CL1-5); HDAC8-IN-1 exhibits cytotoxicity against human lung CL1-5 cells without significant cytotoxicity for normal IMR-90 cells.
MDK-7933
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/01/25 | HY-111342 | HDAC8-IN-1 | | 1 mg | 400元 |
| 2024/01/25 | HY-111342 | MDK-7933
HDAC8-IN-1 | 1417997-93-3 | 5mg | 850元 |
1417997-93-3, MDK-7933 相关搜索:
- 标准品
- 417997-93-3
- (E)-N-羟基-3-(5-甲氧基-[1,1':4',1''-三联苯]-2-基)丙烯酰胺
- 化合物HDAC8-IN-1
- (E)-N-羟基-3-(5-甲氧基-[1,1':4',1''-三联苯]-2-基)丙烯酰胺
- 1417997-93-3
- (E)-N-Hydroxy-3-(5-methoxy-[1,1':4',1''-terphenyl]-2-yl)acrylamide
- HDAC8-IN-1(22d)
- HDAC-8-IN-1,HDAC8IN1,Histone deacetylases,Inhibitor,inhibit,HDAC,HDAC8 IN 1
- HDAC8-IN-1
- 22d
- (E)-N-hydroxy-4-methoxy-2-(biphenyl-4-yl)cinnamamide
- HDAC8-IN-1 ,MDK7933
- MDK-7933
- HDAC8 inhibitor 1
- CS-2693
- HDAC8 inhibitor 22d
- HDAC8-IN-22d
- 2-Propenamide, N-hydroxy-3-(5-methoxy[1,1':4',1''-terphenyl]-2-yl)-, (2E)-
- (2E)-N-Hydroxy-3-(5-methoxy[1,1':4',1''-terphenyl]-2-yl)-2-propenamide
- (E)-N-Hydroxy-3-(5-methoxy-[1,1':4',1''-terphenyl]-2-yl)acrylamide
- INVIVO-7933