党参炔苷
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- CAS号:
- 129277-38-9
- 英文名:
- Lobetyolin
- 英文别名:
- β-D-Glucopyranoside, (1R,2R,7E)-2-hydroxy-1-[(1E)-5-hydroxy-1-pentenyl]-7-nonene-3,5-diynyl (9CI)
- 中文名:
- 党参炔苷
- 中文别名:
- CBNumber:
- CB24808608
- 分子式:
- C20H28O8
- 分子量:
- 396.44
- MOL File:
- 129277-38-9.mol
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党参炔苷化学性质
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沸点:
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698.5±55.0 °C(Predicted)
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密度:
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1.35±0.1 g/cm3(Predicted)
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酸度系数(pKa):
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11.39±0.20(Predicted)
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形态:
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Solid
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颜色:
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White to yellow
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党参炔苷性质、用途与生产工艺
Lobetyolin 是一种分离自 Codonopsis pilosula 的生物活性化合物。Lobetyolin 具有抗炎，抗氧化和黄嘌呤氧化酶抑制活性。Lobetyolin 还通过抑制 ASCT2 介导的谷氨酰胺代谢来诱导细胞凋亡。
Lobetyolin is derived from
Codonopsis pilosula
and has antioxidative effect.
MUC5AC
gene expression induced by phorbol 12-myristate 13-acetate (PMA) from NCI-H292 cells is inhibited by pretreatment with Lobetyolin, lobetyol or methyl linoleate. Lobetyolin does not affect PMA-induced MUC5AC production from NCI-H292 cells. The amounts of mucin in the cells of Lobetyolin-treated cultures are 100±25%, 487±33%, 524±38%, 411±24%, and 402±45% for control, 10 ng/mL of PMA alone, PMA plus Lobetyolin 1 μM, PMA plus Lobetyolin 10 μM, and PMA plus Lobetyolin 100 μM, respectively.
党参炔苷
上下游产品信息
上游原料
下游产品
129277-38-9, 党参炔苷 相关搜索:
- 129277-38-9
- β-D-Glucopyranoside, (1R,2R,7E)-2-hydroxy-1-[(1E)-5-hydroxy-1-pentenyl]-7-nonene-3,5-diynyl (9CI)