566169-97-9
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- CAS号:
- 566169-97-9
- 英文名:
- 4-(6-Bromo-2-benzothiazolyl)benzenamine
- 英文别名:
- 4-(6-Bromobenzo[d]thiazol-2-yl)aniline;4-(6-Bromo-2-benzothiazolyl)benzenamine;Benzenamine, 4-(6-bromo-2-benzothiazolyl)-
- 中文名:
- 566169-97-9
- 中文别名:
- 4-(6-溴苯并[D]噻唑-2-基)苯胺
- CBNumber:
- CB34797015
- 分子式:
- C13H9BrN2S
- 分子量:
- 305.19
- MOL File:
- 566169-97-9.mol
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566169-97-9化学性质
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储存条件:
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Store at -20°C
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溶解度:
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Soluble in DMSO
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566169-97-9性质、用途与生产工艺
4-(6-Bromo-2-benzothiazolyl)benzenamine是β-淀粉样蛋白 (β-amyloid) 的PET（正电子发射断层扫描）示踪剂，可用于诊断神经疾病，如阿尔茨海默病和唐氏综合征。
4-(6-Bromo-2-benzothiazolyl)benzenamine (compound 6l) plus ultraviolet A (UVA) can induce caspase-3 activity, poly(ADP-ribose)polymerase cleavage, M30 positive CytoDeath staining, and subsequent apoptotic cell death. Treatment of A375 cells with 4-(6-Bromo-2-benzothiazolyl)benzenamine plus UVA results in a decrease in mitochondrial membrane potential (ΔΨ
mt
), oxidative phosphorylation system (OXPHOS) subunits, and adenosine triphosphate (ATP) but an increase in mitochondrial DNA 4977-bp deletion via reactive oxygen species (ROS) generation. Transmission electron microscopy (TEM) observations also show major ultrastructural alterations of mitochondria.
4-(6-Bromo-2-benzothiazolyl)benzenamine plus UVA is shown to reduce murine melanoma size in a mouse model. 4-(6-Bromo-2-benzothiazolyl)benzenamine-PDT may serve as a potential ancillary modality for the treatment of melanoma.
566169-97-9
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上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/01/25 | HY-111514 | 4-(6-Bromo-2-benzothiazolyl)benzenamine | | 5 mg | 500元 |
| 2024/01/25 | HY-111514 | 566169-97-9
4-(6-Bromo-2-benzothiazolyl)benzenamine | 566169-97-9 | 10mg | 800元 |
566169-97-9, 566169-97-9 相关搜索:
- 4-(6-溴苯并[D]噻唑-2-基)苯胺
- 566169-97-9
- 4-(6-Bromobenzo[d]thiazol-2-yl)aniline
- Benzenamine, 4-(6-bromo-2-benzothiazolyl)-
- 4-(6-Bromo-2-benzothiazolyl)benzenamine