566169-97-9
| 中文名称 | 566169-97-9 |
|---|---|
| 中文同义词 | 4-(6-溴苯并[D]噻唑-2-基)苯胺 |
| 英文名称 | 4-(6-Bromo-2-benzothiazolyl)benzenamine |
| 英文同义词 | 4-(6-Bromo-2-benzothiazolyl)benzenamine;Benzenamine, 4-(6-bromo-2-benzothiazolyl)-;4-(6-Bromobenzo[d]thiazol-2-yl)aniline |
| CAS号 | 566169-97-9 |
| 分子式 | C13H9BrN2S |
| 分子量 | 305.19 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | 566169-97-9.mol |
| 结构式 |  |
566169-97-9 性质
| 储存条件 | Store at -20°C |
|---|---|
| 溶解度 | 溶于二甲基亚砜 |
β-amyloid
4-(6-Bromo-2-benzothiazolyl)benzenamine (compound 6l) plus ultraviolet A (UVA) can induce caspase-3 activity, poly(ADP-ribose)polymerase cleavage, M30 positive CytoDeath staining, and subsequent apoptotic cell death. Treatment of A375 cells with 4-(6-Bromo-2-benzothiazolyl)benzenamine plus UVA results in a decrease in mitochondrial membrane potential (ΔΨ mt ), oxidative phosphorylation system (OXPHOS) subunits, and adenosine triphosphate (ATP) but an increase in mitochondrial DNA 4977-bp deletion via reactive oxygen species (ROS) generation. Transmission electron microscopy (TEM) observations also show major ultrastructural alterations of mitochondria.
4-(6-Bromo-2-benzothiazolyl)benzenamine plus UVA is shown to reduce murine melanoma size in a mouse model. 4-(6-Bromo-2-benzothiazolyl)benzenamine-PDT may serve as a potential ancillary modality for the treatment of melanoma.
安全信息
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2024/01/25 | HY-111514 | 4-(6-Bromo-2-benzothiazolyl)benzenamine | 5 mg | 500元 | |
| 2024/01/25 | HY-111514 | 566169-97-9 4-(6-Bromo-2-benzothiazolyl)benzenamine | 566169-97-9 | 10mg | 800元 |