丁呋洛尔盐酸盐
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- CAS号:
- 60398-91-6
- 英文名:
- (±)-alpha-[[(tert-butyl)amino]methyl]-7-ethyl-2-benzofuranmethanol hydrochloride
- 英文别名:
- Einecs 262-216-3;KJBONRGCLLBWCJ-UHFFFAOYSA-O;Bufuralol hydrochloride (Ro 3-4787);α-[(tert-Butylamino)methyl]-7-ethyl-2-benzofuranmethanol hydrochloride;(1)-alpha-(((tert-Butyl)amino)methyl)-7-ethyl-2-benzofuranmethanolhydr ochloride
- 中文名:
- 丁呋洛尔盐酸盐
- 中文别名:
- 盐酸丁呋喃洛尔;化合物 T21684
- CBNumber:
- CB4939096
- 分子式:
- C16H24ClNO2
- 分子量:
- 297.82026
- MOL File:
- 60398-91-6.mol
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丁呋洛尔盐酸盐化学性质
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熔点:
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143-146 °C
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储存条件:
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2-8°C
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溶解度:
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H2O: soluble
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形态:
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solid
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颜色:
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white to off-white
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丁呋洛尔盐酸盐性质、用途与生产工艺
Bufuralol hydrochloride (Ro 3-4787 hydrochloride) 是一种有效的非选择性，具有口服活性的 β-肾上腺素受体 (β-adrenoreceptor) 拮抗剂，具有部分激动剂活性。Bufuralol hydrochloride 是一种 CYP2D6 探针的底物。
Bufuralol is widely used in the characterization of CYP2D6 activity, and possesses aromatic rings and a basic nitrogen that are characteristic of CYP2D6 substrates.
Bufuralol metabolism mediated by NADPH exhibits biphasic kinetics and is less efficient than that observed in the presence of cumene hydroperoxide (CuOOH) in and monkey intestines, in agreement with the observations in the livers.
丁呋洛尔盐酸盐
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60398-91-6, 丁呋洛尔盐酸盐 相关搜索:
- Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
- 盐酸丁呋喃洛尔
- 化合物 T21684
- 60398-91-6
- Bufuralol hydrochloride (Ro 3-4787)
- KJBONRGCLLBWCJ-UHFFFAOYSA-O
- Einecs 262-216-3
- α-[(tert-Butylamino)methyl]-7-ethyl-2-benzofuranmethanol hydrochloride
- (1)-alpha-(((tert-Butyl)amino)methyl)-7-ethyl-2-benzofuranmethanolhydr ochloride