1-(2-脱氧-beta-呋喃核糖基)-5-碘-2-嘧啶酮
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- CAS号:
- 93265-81-7
- 英文名:
- 5-Iodo-2-pyrimidinone-2'-deoxyribose
- 英文别名:
- IPdR;Ropidoxuridine;Idoxuridine Impurity 2;Idoxuridine Deoxy Impurity;5-Iodo-2-pyrimidinone-2'-deoxyribose;5-Iodo-2-pyrimidinone-2'-deoxyribose;1-(2-deoxy-beta-ribofuranosyl)-5-iodo-2-pyrimidinone;2(1H)-Pyrimidinone, 1-(2-deoxy-β-D-erythro-pentofuranosyl)-5-iodo-;1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidin-2-one
- 中文名:
- 1-(2-脱氧-beta-呋喃核糖基)-5-碘-2-嘧啶酮
- 中文别名:
- 化合物 T16785;1-(2-脱氧-BETA-呋喃核糖基)-5-碘-2-嘧啶酮
- CBNumber:
- CB51366724
- 分子式:
- C9H11IN2O4
- 分子量:
- 338.1
- MOL File:
- 93265-81-7.mol
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1-(2-脱氧-beta-呋喃核糖基)-5-碘-2-嘧啶酮化学性质
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熔点:
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160-170 °C (decomp)
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沸点:
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478.6±55.0 °C(Predicted)
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密度:
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2.22±0.1 g/cm3(Predicted)
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储存条件:
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Store at -20°C
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溶解度:
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Soluble in DMSO
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酸度系数(pKa):
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14.03±0.60(Predicted)
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1-(2-脱氧-beta-呋喃核糖基)-5-碘-2-嘧啶酮性质、用途与生产工艺
Ropidoxuridine (IPdR) 是一种新型口服，卤化胸苷类似物，有希望用于人类肿瘤的增敏剂。
Ropidoxuridine is an orally bioavailable pro-drug of IUdR (5-iodo-2'-deoxyuridine). Ropidoxuridine demonstrates strong synergy effects with Alisertib at clinically relevant concentrations.
In an orthotopic tumor model, Ropidoxuridine (750 mg/kg/day) and Alisertib (30 mg/kg/day) demonstrate strong synergy effects.
1-(2-脱氧-beta-呋喃核糖基)-5-碘-2-嘧啶酮
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
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| 2024/04/30 | HY-13742 | Ropidoxuridine | | 1 mg | 1200元 |
| 2024/04/30 | HY-13742 | 1-(2-脱氧-beta-呋喃核糖基)-5-碘-2-嘧啶酮
Ropidoxuridine | 93265-81-7 | 5mg | 3000元 |
1-(2-脱氧-beta-呋喃核糖基)-5-碘-2-嘧啶酮
生产厂家
93265-81-7, 1-(2-脱氧-beta-呋喃核糖基)-5-碘-2-嘧啶酮 相关搜索:
- 化合物 T16785
- 1-(2-脱氧-BETA-呋喃核糖基)-5-碘-2-嘧啶酮
- 93265-81-7
- 5-Iodo-2-pyrimidinone-2'-deoxyribose
- 2(1H)-Pyrimidinone, 1-(2-deoxy-β-D-erythro-pentofuranosyl)-5-iodo-
- Idoxuridine Impurity 2
- Idoxuridine Deoxy Impurity
- 1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidin-2-one
- Ropidoxuridine
- IPdR
- 5-Iodo-2-pyrimidinone-2'-deoxyribose
- 1-(2-deoxy-beta-ribofuranosyl)-5-iodo-2-pyrimidinone