β-Amyloid (10-35), amide
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- CAS号:
- 181427-66-7
- 英文名:
- β-Amyloid (10-35), amide
- 英文别名:
- β-Amyloid (10-35);β-Amyloid (10-35), amide;Bate-Amyloid (10-35),amide;L-Methioninamide, L-tyrosyl-L-α-glutamyl-L-valyl-L-histidyl-L-histidyl-L-glutaminyl-L-lysyl-L-leucyl-L-valyl-L-phenylalanyl-L-phenylalanyl-L-alanyl-L-α-glutamyl-L-α-aspartyl-L-valylglycyl-L-seryl-L-asparaginyl-L-lysylglycyl-L-alanyl-L-isoleucyl-L-isoleucylglycyl-L-leucyl-
- 中文名:
- β-Amyloid (10-35), amide
- 中文别名:
- Β淀粉样肽片段多肽(10-35), AMIDE;Β-AMYLOID (10-35), AMIDE
- CBNumber:
- CB54713860
- 分子式:
- C133H205N35O36S
- 分子量:
- 2902.37
- MOL File:
- 181427-66-7.mol
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β-Amyloid (10-35), amide化学性质
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沸点:
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2714.6±65.0 °C(Predicted)
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密度:
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1.294±0.06 g/cm3(Predicted)
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储存条件:
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Store at -20°C
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溶解度:
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Soluble in DMSO
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β-Amyloid (10-35), amide性质、用途与生产工艺
β-Amyloid (10-35), amide 是一种含有 26 个氨基酸的多肽,由 β-Amyloid 肽的 10-35 残基组成。β-Amyloid (10-35) 是阿尔兹海默症淀粉样斑块 (Alzheimer’s disease) 的主要组成成分。
β-Amyloid (10-35) is selected based on the following considerations: (1) β-Amyloid (10-35) incorporates the core region, point mutations of which significantly obstruct fibril formation and have been used to generate inhibitors of fibrillogenesis; (2) β-Amyloid (10-35) retains the ability to add to bona fide Alzheimer’s plaques, in contrast to other truncated peptides, and forms fibrils morphologically similar to those of the full length peptide; (3) Of most importance, the full length peptide, Aβ
(1-42)
, is intractable for the controlled formation of fibrils from aqueous media because at the earliest time points, some of the peptide exists as an amorphous precipitate. In contrast, the use of β-Amyloid (10-35) allows the reproducible and controlled formation of fibrils from aqueous solutions, under defined conditions of pH, ionic strength, and peptide concentration and thus yields the required homogeneous fibrils.
β-Amyloid (10-35), amide
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下游产品
更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
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2023/03/20 | HY-P1567 | β-Amyloid (10-35), amide β-Amyloid (10-35), amide | 181427-66-7 | 1mg | 1000元 |
2023/03/20 | HY-P1567 | β-Amyloid (10-35), amide β-Amyloid (10-35), amide | 181427-66-7 | 5mg | 3300元 |
β-Amyloid (10-35), amide
生产厂家
181427-66-7, β-Amyloid (10-35), amide 相关搜索:
- Β淀粉样肽片段多肽(10-35), AMIDE
- Β-AMYLOID (10-35), AMIDE
- 181427-66-7
- Bate-Amyloid (10-35),amide
- L-Methioninamide, L-tyrosyl-L-α-glutamyl-L-valyl-L-histidyl-L-histidyl-L-glutaminyl-L-lysyl-L-leucyl-L-valyl-L-phenylalanyl-L-phenylalanyl-L-alanyl-L-α-glutamyl-L-α-aspartyl-L-valylglycyl-L-seryl-L-asparaginyl-L-lysylglycyl-L-alanyl-L-isoleucyl-L-isoleucylglycyl-L-leucyl-
- β-Amyloid (10-35)
- β-Amyloid (10-35), amide