β-Amyloid (10-35), amide
中文名称 | β-Amyloid (10-35), amide |
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中文同义词 | Β-AMYLOID (10-35), AMIDE;Β淀粉样肽片段多肽(10-35), AMIDE |
英文名称 | β-Amyloid (10-35), amide |
英文同义词 | β-Amyloid (10-35), amide;β-Amyloid (10-35);L-Methioninamide, L-tyrosyl-L-α-glutamyl-L-valyl-L-histidyl-L-histidyl-L-glutaminyl-L-lysyl-L-leucyl-L-valyl-L-phenylalanyl-L-phenylalanyl-L-alanyl-L-α-glutamyl-L-α-aspartyl-L-valylglycyl-L-seryl-L-asparaginyl-L-lysylglycyl-L-alanyl-L-isoleucyl-L-isoleucylglycyl-L-leucyl-;Bate-Amyloid (10-35),amide |
CAS号 | 181427-66-7 |
分子式 | C133H205N35O36S |
分子量 | 2902.37 |
EINECS号 | |
相关类别 | |
Mol文件 | 181427-66-7.mol |
结构式 |
β-Amyloid (10-35), amide 性质
沸点 | 2714.6±65.0 °C(Predicted) |
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密度 | 1.294±0.06 g/cm3(Predicted) |
储存条件 | Store at -20°C |
溶解度 | 溶于二甲基亚砜 |
β-Amyloid (10-35) is selected based on the following considerations: (1) β-Amyloid (10-35) incorporates the core region, point mutations of which significantly obstruct fibril formation and have been used to generate inhibitors of fibrillogenesis; (2) β-Amyloid (10-35) retains the ability to add to bona fide Alzheimer’s plaques, in contrast to other truncated peptides, and forms fibrils morphologically similar to those of the full length peptide; (3) Of most importance, the full length peptide, Aβ (1-42) , is intractable for the controlled formation of fibrils from aqueous media because at the earliest time points, some of the peptide exists as an amorphous precipitate. In contrast, the use of β-Amyloid (10-35) allows the reproducible and controlled formation of fibrils from aqueous solutions, under defined conditions of pH, ionic strength, and peptide concentration and thus yields the required homogeneous fibrils.
安全信息
更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
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2023/03/20 | HY-P1567 | β-Amyloid (10-35), amide β-Amyloid (10-35), amide | 181427-66-7 | 1mg | 1000元 |
2023/03/20 | HY-P1567 | β-Amyloid (10-35), amide β-Amyloid (10-35), amide | 181427-66-7 | 5mg | 3300元 |