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OXYTHIAMINE HYDROCHLORIDE

生物活性 靶点 体外研究 OXYTHIAMINE HYDROCHLORIDE 试剂级价格
OXYTHIAMINE HYDROCHLORIDE, 136-16-3, 结构式
OXYTHIAMINE HYDROCHLORIDE
CAS号:
136-16-3
英文名:
OXYTHIAMINE HYDROCHLORIDE
英文别名:
azolium;oxythiamin;oxythiamine;Hydroxythiamin;oxythiamine(1+);OXYTHIAMINE HCL;Thiamine Impurity 19;OXYTHIAMINE HYDROCHLORIDE;Oxythiamine·HCl≥ 99% (assay);Oxythiamine (Hydroxythiamin)
中文名:
OXYTHIAMINE HYDROCHLORIDE
中文别名:
化合物 T12354;硫胺素(维生素B1)杂质19
CBNumber:
CB6428626
分子式:
C12H17Cl2N3O2S
分子量:
338.25
MOL File:
136-16-3.mol

OXYTHIAMINE HYDROCHLORIDE化学性质

密度:
1.2416 (rough estimate)
折射率:
1.6740 (estimate)
储存条件:
−20°C
溶解度:
DMSO : 51.67 mg/mL (194.00 mM)
安全信息
WGK Germany: 3
RTECS号: XJ7034100
毒性: LD50 scu-mus: 1430 mg/kg PCJOAU16,848,82

OXYTHIAMINE HYDROCHLORIDE性质、用途与生产工艺

生物活性

Oxythiamine 是一种抗代谢物和维生素B1 (vitamin B1)拮抗剂，也是众所周知的硫铵 (thiamine) 拮抗剂和转酮醇酶 (transketolase) 抑制剂。

靶点

Vitamin B1, Thiamine, Transketolase.

体外研究

Oxythiamine, an antimetabolite and a vitamin B1 antagonist, is a well-known thiamine antagonist and inhibitor of transketolase. Oxythiamine alters protein expression in a dose dependent manner. The level of alpha-enolase is increased by Oxythiamine treatment, while expression of 14-3-3 protein beta/alpha is suppressed by Oxythiamine at a stratified dose. Oxythiamine causes dynamic changes of total protein expression in time dependent fashion. Oxythiamine suppresses expression of cellular phosphor proteins significantly.

OXYTHIAMINE HYDROCHLORIDE 上下游产品信息

上游原料

下游产品

OXYTHIAMINE HYDROCHLORIDE 试剂级价格

更新日期产品编号产品名称CAS编号包装价格
2024/01/25HY-107430Oxythiamine5 mg218元
2024/01/25HY-107430Oxythiamine10 mg350元

OXYTHIAMINE HYDROCHLORIDE 生产厂家

全球有 19家供应商   OXYTHIAMINE HYDROCHLORIDE国内生产厂家
供应商联系电话电子邮件国家产品数优势度
湖北扬信医药科技有限公司 15374522761 3003392093@qq.com 中国 7851 55
江苏艾康生物医药研发有限公司 025-66113011 18112977050 sales01@aikonchem.com 中国 16028 58
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 marketing@targetmol.com 美国 19892 58
上海源溪生物科技有限公司 021-58447131 13564518121 sales@dcchemicals.com 中国 9414 58
ChemeGen 中国 18818260767 sales@chemegen.com 中国 11289 58
上海弘渠生物医药科技有限公司 88888888888 hongquchem@qq.com 中国 5132 58
天津普西唐生物医药科技有限公司 010-60605840 15801484223 psaitong@jm-bio.com 中国 29834 58
开封明仁药业有限公司 0371-65741762 sales@hasunny.com 中国 2380 58
上海麦克林生化科技股份有限公司 021-50706066 15221275939 shenlinxing@macklin.cn 中国 29803 58
湖北国云福瑞科技有限公司 18162595016 3287908757@qq.com 中国 10015 58
 

136-16-3, OXYTHIAMINE HYDROCHLORIDE 相关搜索:

4-甲基-5-(beta-羟乙基)噻唑 5-甲基嘧啶-4-醇 5-嘧啶甲胺 2-甲基嘧啶-4-醇
  • C12H16N3O2S
  • C12H15N3O2SHCl
  • 硫胺素(维生素B1)杂质19
  • 化合物 T12354
  • 136-16-3
  • Thiamine Impurity 19
  • Oxythiamine DISCONTINUED. Please see O878508.
  • Hydroxythiamin
  • Oxythiamine (Synonyms: Hydroxythiamin)
  • Oxythiamine (Hydroxythiamin)
  • OXYTHIAMINE HYDROCHLORIDE
  • OXYTHIAMINE HCL
  • OXYTHIAMINE CHLORIDE HYDROCHLORIDE
  • 5-(2-Hydroxyethyl)-3-[(4-hydroxy-2-methyl-5-pyrimidinyl)methyl]-4-methylthiazol-3-ium
  • 3-[(3,4-Dihydro-2-methyl-4-oxopyrimidine-5-yl)methyl]-5-(2-hydroxyethyl)-4-methylthiazolium
  • 3-[(1,4-Dihydro-2-methyl-4-oxopyrimidin-5-yl)methyl]-5-(2-hydroxyethyl)-4-methylthiazol-3-ium
  • oxythiamine
  • oxythiamin
  • azolium
  • 5-(2-hydroxyethyl)-3-((4-hydroxy-2-methyl-5-pyrimidinyl)methyl)-4-methyl-thi
  • 5-[2-HYDROXYETHYL]-3-[4-HYDROXY-2-METHYL-5-PYRIMIDINYLMETHYL]-4-METHYLTHIAZOLIUM CHLORIDE HYDROCHLORIDE
  • 5-(2-HYDROXYETHYL)-3-(4-HYDROXY-2-METHYL-5-PYRIMIDINYLMETHYL)-4-METHYLTHIAZOLIUM CHLORIDE
  • thiazolium,5-(2-hydroxyethyl)-3-((4-hydroxy-2-methyl-5-pyrimidinyl)methyl)-4-m
  • oxythiamine(1+)
  • Oxythiamine·HCl≥ 99% (assay)
  • Thiazolium,3-[(3,4-dihydro-2-methyl-4-oxo-5-pyrimidinyl)methyl]-5-(2-hydroxyethyl)-4-methyl-
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