(1R,2R)-2-(3,4-二氟苯基)环丙烷羧酸乙酯

(1R,2R)-2-(3,4-二氟苯基)环丙烷羧酸乙酯性质、用途与生产工艺

用途

(1R,2R)-2-(3,4-二氟苯基)环丙烷羧酸乙酯是合成替卡格雷(ticagrelor)的关键中间体。替卡格雷，化学名[1S-[1α,2α,3β(1S,2R),5β]]-3-[7-[2-(3,4-二氟苯基)-环丙胺基]-5-(丙硫基)-3H-1,2,3-三唑并[4,5-d]嘧啶-3-基]-5-(2-羟乙氧基)环戊烷-1,2-二醇，是由阿斯利康公司(AstraZenecaAB)研发的一种口服抗血小板药物。该药能可逆地作用于ADPP2Y12受体，对ADP引起的血小板聚集有明显的抑制作用，且口服起效迅速，临床用于降低急性冠状动脉综合征患者的血栓性心血管事件发生率。

(1R,2R)-2-(3,4-二氟苯基)环丙烷羧酸乙酯 上下游产品信息

上游原料

下游产品

(1R,2R)-2-(3,4-二氟苯基)环丙烷羧酸乙酯 生产厂家

1006376-61-9, (1R,2R)-2-(3,4-二氟苯基)环丙烷羧酸乙酯 相关搜索:

• 杂质对照品
• 替格瑞洛杂质120
• 替格瑞洛(替卡格雷)杂质120
• (1R,2R)-2-(3,4-二氟苯基)环丙烷甲酸乙酯
• 替卡格雷杂质56
• 替卡格雷杂质82
• 替格瑞洛杂质 135
• 替卡格雷化合物D
• (1R,2R)-2-(3,4-二氟苯基)环丙烷羧酸乙酯
• 1006376-61-9
• Ethyl (1R,2R)-2-(3,4-Difluorophenyl)cyclopropanecarboxylate
• (1R,2R)-2-(3,4-Difluorophenyl)cyclopropan-1-carboxylic acid ethyl ester
• Ticagrelor Impurity 120
• (1R,2R)-trans-Ethyl 2-(3,4-difluorophenyl)cyclopropanecarboxylate
• Ticagrelor Impurity 135
• Ticagrelor impurity 32/ethyl(1R,2R)-2-(3,4-difluorophenyl)cyclopropane-1-carboxylate
• Ticagrelor-21
• (1S,2S,3S,5S)-3-(7-hydroxy-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol
• ethyl(1R,2R)-2-(3,4-difluorophenyl)cyclopropane-1-carboxylate
• (1R,2R)-2-(3,4-Difluorophenyl)cyclopropanecarboxylic acid ethyl ester
• Cyclopropanecarboxylic acid, 2-(3,4-difluorophenyl)-, ethyl ester,(1R,2R)-
• (1R,2R)-ethyl2-(3,4-difluorophenyl)cyclopropane carboxylate