6alpha,9-difluoro-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 17,21-di(acetate)

CAS号:: 23641-05-6

英文名:: 6alpha,9-difluoro-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 17,21-di(acetate)

英文别名:: Einecs 245-799-9;Fluocinolone Acetonide Impurity 23;17,21-Diacetyloxy-6,9-dilfuoro-11-hydroxypregna-1,4-diene-3,20-dione;17,21-Bis(acetyloxy)-6α,9-difluoro-11β-hydroxypregna-1,4-diene-3,20-dione;)-17,21-Bis(acetyloxy)-6,9-difluoro-11-hydroxy-pregna-1,4-diene-3,20-dione;6,9-Difluoro-11,17,21-trihydroxypregn-a-1,4-diene-3,20-dione-17,21-diacetate;(6α,11β)-17,21-Bis(acetyloxy)-6,9-difluoro-11-hydroxy-pregna-1,4-diene-3,20-dione;(6α,11β)-17,21-Bis(acetyloxy)-6,9-difluoro-11-hydroxy-pregna-1,4-diene-3,20-dione;Pregna-1,4-diene-3,20-dione, 17,21-bis(acetyloxy)-6,9-difluoro-11-hydroxy-, (6α,11β)-;6alpha,9-difluoro-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 17,21-di(acetate)

中文名:: 6alpha,9-difluoro-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 17,21-di(acetate)

中文别名:: 丙酮氟洛松杂质23;6Α,9Α-二氟孕甾-1,4-二烯-11Β,17Α,21-三醇-3,20-二酮-17,21-二醋酸酯

CBNumber:: CB7917956

分子式:: C25H30F2O7

分子量:: 480.5

MOL File:: 23641-05-6.mol

化学性质安全信息用途供应商 10

6alpha,9-difluoro-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 17,21-di(acetate)化学性质

熔点:: 280-283 °C

沸点:: 580.9±50.0 °C(Predicted)

密度:: 1.33±0.1 g/cm3(Predicted)

溶解度:: DMSO (Slightly)

形态:: Solid

酸度系数(pKa):: 12.63±0.70(Predicted)

颜色:: White to Off-White

安全信息

6alpha,9-difluoro-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 17,21-di(acetate)性质、用途与生产工艺

化学性质

结晶。

用途

肤轻松醋酸酯的中间体。

生产方法

可用11α,17α,21-三羟基孕甾-4-烯-3,20-二酮（即表氢化可的松）经（21-位羟基）乙酰化、（11-位羟基）磺酰化并消除[形成9（11）-双键]、（17α-羟基及3-位酮基）乙酰化（4-位双键转化成3-位及5-位双键）、（6β-位）氟化、水解（去除3-位乙酰基），（3-位、5-位双键转回3-位酮基及4-位双键）、（6β-氟）转位、[9（11）-双键）环氧化、（环氧基上氟化氢）加成（引入11β-羟基-及9α-氟）、脱氢（形成1-位双键）制得该品。

6alpha,9-difluoro-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 17,21-di(acetate) 上下游产品信息

上游原料

氢氟酸 11-表氢化可的松氢化可的松

下游产品

6alpha,9-difluoro-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 17,21-di(acetate) 生产厂家

全球有 10家供应商 6alpha,9-difluoro-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 17,21-di(acetate)国内生产厂家

供应商	联系电话	电子邮件	国家	产品数	优势度
BOC Sciences	1-631-485-4226; 16314854226	info@bocsci.com	美国	14059	65
BOC Sciences	16314854226	info@bocsci.com	美国	9926	65
广州隽沐生物科技股份有限公司	17825480238	3008233717@qq.com	中国	9844	12
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	中国	28180	58
湖北摩科化学有限公司	18627756402	3001051413@qq.com	中国	10014	58
安耐吉化学&3A（安徽泽升科技有限公司）	021-58432009 400-005-6266	marketing1@energy-chemical.com	中国	44894	58
深圳市江川医药技术有限公司	13670046396	ORDERS@QCSRM.COM	中国	18810	58

23641-05-6, 6alpha,9-difluoro-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 17,21-di(acetate) 相关搜索:

FLURANDRENOLONEACETATE 9beta,11beta-epoxy-6alpha-fluoro-21-hydroxy-16alpha,17-(isopropylidenedioxy)pregna-1,4-diene-3,20-dione21-acetate 氟轻松酮丙酮杂质4 FluocinoloneAcetonide-21-aldehyde 6-alpha,9-alpha-difluoro-11-beta,16-alpha,17-alpha,21-tetrahydroxypregna-1,4-diene-3,20-dione 醋酸氟轻松 9a-Fluoro-11,6a,17a,21-Tetrahydroxy-Pregna-4-ene-3,20-Dione 醋酸氟轻松杂质B 6-alpha-fluoro-21-hydroxy-16-alpha,17-alpha-isopropylidenedioxypregn-4-ene-3,20-dione FLUOCORTOLONEHEXANOATE 氟轻松酮丙酮杂质2 (6α,11β,16α)-6,9-Difluoro-11,21-dihydroxy-21-Methoxy-16,17-[(1-Methylethylidene)bis(oxy)]-pregna-1,4-diene-3,20-dione 醋酸氟轻松曲安奈德氟轻松杂质E(EP) 21-Acetyl-6β-fluorotriamcinoloneAcetonide 21-乙酰氧基-6Α,9Α-二氟-11Β,16Α,17Α,三羟基孕甾-1,4-二烯-3,20-二酮 (6ALPHA,11BETA,16ALPHA,17ALPHA)-6,9-二氟-11-羟基-16,17-[(1-甲基亚乙基)二(氧基)]-3,20-二氧代孕甾-1,4-二烯-21-酸

丙酮氟洛松杂质23
6Α,9Α-二氟孕甾-1,4-二烯-11Β,17Α,21-三醇-3,20-二酮-17,21-二醋酸酯
23641-05-6
(6α,11β)-17,21-Bis(acetyloxy)-6,9-difluoro-11-hydroxy-pregna-1,4-diene-3,20-dione
)-17,21-Bis(acetyloxy)-6,9-difluoro-11-hydroxy-pregna-1,4-diene-3,20-dione
Fluocinolone Acetonide Impurity 23
Pregna-1,4-diene-3,20-dione, 17,21-bis(acetyloxy)-6,9-difluoro-11-hydroxy-, (6α,11β)-
(6α,11β)-17,21-Bis(acetyloxy)-6,9-difluoro-11-hydroxy-pregna-1,4-diene-3,20-dione
Einecs 245-799-9
17,21-Bis(acetyloxy)-6α,9-difluoro-11β-hydroxypregna-1,4-diene-3,20-dione
6,9-Difluoro-11,17,21-trihydroxypregn-a-1,4-diene-3,20-dione-17,21-diacetate
17,21-Diacetyloxy-6,9-dilfuoro-11-hydroxypregna-1,4-diene-3,20-dione
6alpha,9-difluoro-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 17,21-di(acetate)