KN-92 盐酸盐
|
|
|
- CAS号:
- 1431698-47-3
- 英文名:
- KN-92 (hydrochloride)
- 英文别名:
- CS-1448;KN92-HCl;KN-92 (hydrochloride);KN 92 HYDROCHLORIDE; KN92 HYDROCHLORIDE;N-(2-(((3-(4-Chlorophenyl)allyl)(methyl)amino)methyl)phenyl)-4-methoxybenzenesulfonamide hydrochloride;Inhibitor,derivative,experimental,inactive,KN-92,KN92 hydrochloride,KN92,inhibit,analog,KN 92 hydrochloride,control,KN 92
- 中文名:
- KN-92 盐酸盐
- 中文别名:
- KN-92 盐酸盐;N-(2-(((3-(4-氯苯基)烯丙基)(甲基)氨基)甲基)苯基)-4-甲氧基苯磺酰胺 盐酸盐
- CBNumber:
- CB82591540
- 分子式:
- C24H26Cl2N2O3S
- 分子量:
- 493.44584
- MOL File:
- 1431698-47-3.mol
|
|
|
KN-92 盐酸盐化学性质
-
储存条件:
-
Inert atmosphere,Store in freezer, under -20°C
-
|
-
溶解度:
-
≥24.65 mg/mL in DMSO; insoluble in H2O; ≥11.73 mg/mL in EtOH with gentle warming and ultrasonic
-
|
-
形态:
-
solid
-
|
-
颜色:
-
White to off-white
-
|
KN-92 盐酸盐性质、用途与生产工艺
KN-92 hydrochloride 是 KN-93 的非活性衍生物，不具有 CaM 激酶抑制活性。KN-92 hydrochloride 可作为对照化合物用于阐明 KN-93 的拮抗活性。KN-93 可渗透细胞，可逆和竞争性的 CaMKII 抑制剂。
KN-93 (5-50μM; 24 hours) inhibits LX-2 cell growth and KN-92 (5-50μM; 24 hours) is ineffective in blocking cell growth.
The analysis of cell cycle regulator expression reveals that KN-93 rather than KN-92 reduced the expression of p53 and p21.
Cell Viability Assay
|
Cell Line:
|
Human hepatic stellate cells (LX-2)
|
|
Concentration:
|
5-50 μM
|
|
Incubation Time:
|
24 hours
|
|
Result:
|
Ineffective in blocking cell growth.
|
KN-92 盐酸盐
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/08/19 | HY-15517B | KN-92 盐酸盐
KN-92 hydrochloride | | 1 mg | 400元 |
| 2024/08/19 | HY-15517B | KN-92 盐酸盐
KN-92 hydrochloride | 1431698-47-3 | 5mg | 1300元 |
1431698-47-3, KN-92 盐酸盐 相关搜索:
- C24H26Cl2N2O3S
- C24H25ClN2O3SHCl
- N-(2-(((3-(4-氯苯基)烯丙基)(甲基)氨基)甲基)苯基)-4-甲氧基苯磺酰胺 盐酸盐
- KN-92 盐酸盐
- 1431698-47-3
- N-(2-(((3-(4-Chlorophenyl)allyl)(methyl)amino)methyl)phenyl)-4-methoxybenzenesulfonamide hydrochloride
- Inhibitor,derivative,experimental,inactive,KN-92,KN92 hydrochloride,KN92,inhibit,analog,KN 92 hydrochloride,control,KN 92
- CS-1448
- KN 92 HYDROCHLORIDE; KN92 HYDROCHLORIDE
- KN92-HCl
- KN-92 (hydrochloride)