Azadibenzocyclooctyne-PEG4-acid
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- CAS号:
- 1870899-46-9
- 英文名:
- Azadibenzocyclooctyne-PEG4-acid
- 英文别名:
- DBCO-NHCO-PEG4-acid;DBCO-NHCO-PEG5-acid;DBCO-PEG4-CH2CH2COOH;DBCO-NH-PEG4-CH2CH2COOH;DBCO-PEG5-acid,DBCO-PEG5-COOH;Azadibenzocyclooctyne-PEG4-acid;4,7,10,13,16-Pentaoxa-20-azatricosanoic acid, 23-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-19,23-dioxo-
- 中文名:
- Azadibenzocyclooctyne-PEG4-acid
- 中文别名:
- 二苯基环辛炔-五聚乙二醇-羧酸;二苯并环辛炔-五聚乙二醇-羧酸;氮杂二苯并环辛炔四聚乙二醇羧乙基;二苯并环辛炔-NHCO-五聚乙二醇-羧酸;二苯并环辛炔-五聚乙二醇-羧基,DBCO-PEG5-ACID,DBCO-PEG5-COOH
- CBNumber:
- CB83155020
- 分子式:
- C32H40N2O9
- 分子量:
- 596.67
- MOL File:
- 1870899-46-9.mol
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Azadibenzocyclooctyne-PEG4-acid化学性质
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沸点:
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855.9±65.0 °C(Predicted)
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密度:
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1.26±0.1 g/cm3(Predicted)
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溶解度:
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Soluble in Water, DMSO, DMF, DCM
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酸度系数(pKa):
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4.28±0.10(Predicted)
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Azadibenzocyclooctyne-PEG4-acid性质、用途与生产工艺
DBCO-Amide-PEG5-acid 是一种 PROTAC 连接桥，属于 PEG 类。DBCO-Amide-PEG5-acid 可用于合成一系列 PROTAC 分子。DBCO-Amide-PEG5-acid 是一种可降解 (cleavable) 的 ADC 连接桥，用于抗体药物结合物 (ADCs) 的合成。
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
Azadibenzocyclooctyne-PEG4-acid
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Azadibenzocyclooctyne-PEG4-acid
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1870899-46-9, Azadibenzocyclooctyne-PEG4-acid 相关搜索:
- 点击化学
- C32H40N2O9
- 二苯并环辛炔-NHCO-五聚乙二醇-羧酸
- 二苯并环辛炔-五聚乙二醇-羧酸
- 氮杂二苯并环辛炔四聚乙二醇羧乙基
- 二苯基环辛炔-五聚乙二醇-羧酸
- 二苯并环辛炔-五聚乙二醇-羧基,DBCO-PEG5-ACID,DBCO-PEG5-COOH
- 1870899-46-9
- 4,7,10,13,16-Pentaoxa-20-azatricosanoic acid, 23-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-19,23-dioxo-
- DBCO-NHCO-PEG4-acid
- DBCO-PEG5-acid,DBCO-PEG5-COOH
- DBCO-NHCO-PEG5-acid
- DBCO-PEG4-CH2CH2COOH
- DBCO-NH-PEG4-CH2CH2COOH
- Azadibenzocyclooctyne-PEG4-acid