389574-20-3
|
|
|
- CAS号:
- 389574-20-3
- 英文名:
- Prasugrel (Maleic acid)
- 英文别名:
- PCR 4099 (Maleic acid);Prasugrel (Maleic acid)
- 中文名:
- 389574-20-3
- 中文别名:
- 马来酸普拉格雷;化合物 T16572
- CBNumber:
- CB92677072
- 分子式:
- C24H24FNO7S
- 分子量:
- 489.5132632
- MOL File:
- 389574-20-3.mol
|
|
|
389574-20-3化学性质
-
储存条件:
-
Store at -20°C
-
|
-
溶解度:
-
Soluble in DMSO
-
|
-
形态:
-
Powder
-
|
389574-20-3性质、用途与生产工艺
Prasugrel (PCR 4099) Maleic acid，一种噻吩吡啶和前药，抑制血小板功能。Prasugrel Maleic acid 是一种有效的 P2Y12 受体拮抗剂，抑制 ADP 诱导的血小板聚集。
In rat platelets, Prasugrel (PCR 4099) Maleic acid active metabolite inhibits in vitro platelet aggregation induced by adenosine ADP (10μM) with an IC
50
value of 1.8 μM.
Prasugrel (PCR 4099) Maleic acid acts faster and is significantly more potent than Clopidogrel in vivo. Prasugrel hydrochloride is an inactive prodrug that requires metabolic processing in vivo to generate the active antiplatelet metabolite. Prasugrel (PCR 4099) Maleic acid is rapidly absorbed from the gut. After oral administration of standard-loading doses of 60 mg, maximum plasma levels of the active metabolite are achieved within 1 h, effective, maximum inhibition of platelet aggregation at 1-2 h.
389574-20-3
上下游产品信息
上游原料
下游产品
389574-20-3, 389574-20-3 相关搜索:
- 化合物 T16572
- 马来酸普拉格雷
- 389574-20-3
- PCR 4099 (Maleic acid)
- Prasugrel (Maleic acid)