(3β,5β)-3-[(6-Deoxy-3-O-methyl-α-L-glucopyranosyl)oxy]-14-hydroxy-19-oxocard-20(22)-enolid
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- CAS-Nr.
- 1182-87-2
- Bezeichnung:
- (3β,5β)-3-[(6-Deoxy-3-O-methyl-α-L-glucopyranosyl)oxy]-14-hydroxy-19-oxocard-20(22)-enolid
- Englisch Name:
- PERUVOSIDE
- Synonyma:
- Enordin;encordin;Pervoside;peruvosid;PERUVOSIDE;(22)-enolide;PERUVOSIDE(RG);Peruvoside (90%);PERUVOSIDE USP/EP/BP;cannogeninthevetoside
- CBNumber:
- CB0266619
- Summenformel:
- C30H44O9
- Molgewicht:
- 548.66
- MOL-Datei:
- 1182-87-2.mol
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(3β,5β)-3-[(6-Deoxy-3-O-methyl-α-L-glucopyranosyl)oxy]-14-hydroxy-19-oxocard-20(22)-enolid Eigenschaften
- Schmelzpunkt:
- 161-164°C
- alpha
- D22 -71.7° (c = 1.54 in methanol)
- Siedepunkt:
- 540.83°C (rough estimate)
- Dichte
- 1.1277 (rough estimate)
- Brechungsindex
- 1.5500 (estimate)
- storage temp.
- 2-8°C
- Löslichkeit
- Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
- pka
- 12.92±0.70(Predicted)
- Aggregatzustand
- powder
- Farbe
- light yellow
Sicherheit
| Kennzeichnung gefährlicher |
T |
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| R-Sätze: |
23/24/25 |
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| S-Sätze: |
36/37/39-45 |
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| WGK Germany |
3 |
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| RTECS-Nr. |
FH4915000 |
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| Toxizität |
cat,LD50,intravenous,145ug/kg (0.145mg/kg),GASTROINTESTINAL: NAUSEA OR VOMITINGCARDIAC: ARRHYTHMIAS (INCLUDING CHANGES IN CONDUCTION)CARDIAC: CHANGE IN RATE,Archives Internationales de Pharmacodynamie et de Therapie. Vol. 126, Pg. 412, 1960. |
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(3β,5β)-3-[(6-Deoxy-3-O-methyl-α-L-glucopyranosyl)oxy]-14-hydroxy-19-oxocard-20(22)-enolid Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R23/24/25:Giftig beim Einatmen, Verschlucken und Berührung mit der Haut.
S-Sätze Betriebsanweisung:
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
Verwenden
Peruvoside is a cardiac glycoside with the same inotropic and chronotropic effects on heart function as Ouabain (O714500).
Enzyminhibitor
This cardiotonic glycoside or cardenoide (FW = 548.67 g/mol; CAS 1182- 87-2), named systematically as (3b,5b)-3-(6-deoxy-3-O-methyl-a-Lglucopyranosyl)oxyl-14-hydroxy-19-oxocard-20(22)-enolide, a component of neriperside from Thevetia neriifolia (yellow oleander) resembles oubain in its inotropic (force of contraction) and chronotropic (rate of contraction) effects on heart function. Orally administered peruvoside is effective in treating congestive heart failure. Note the structural similarities of the aglycon to digitoxigenin. Target(s): Na+ /K+ -exchanging ATPase.
(3β,5β)-3-[(6-Deoxy-3-O-methyl-α-L-glucopyranosyl)oxy]-14-hydroxy-19-oxocard-20(22)-enolid Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
(3β,5β)-3-[(6-Deoxy-3-O-methyl-α-L-glucopyranosyl)oxy]-14-hydroxy-19-oxocard-20(22)-enolid Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 53)Lieferanten
1182-87-2((3β,5β)-3-[(6-Deoxy-3-O-methyl-α-L-glucopyranosyl)oxy]-14-hydroxy-19-oxocard-20(22)-enolid)Verwandte Suche:
- PERUVOSIDE
- (22)-enolide
- (3β,5β)-3-(6-Deoxy-3-O-methyl-α-L-glucopyranosyl]oxyl)-14-hydroxy-19-oxocard-20(22)-enolide
- 3β-[(6-Deoxy-3-O-methyl-α-L-glucopyranosyl)oxy]-14-hydroxy-19-oxo-5β,14β-card-20(22)-enolide
- Cannogenin α-L-thevetoside
- Enordin
- Pervoside
- (3β,5β)-3-[(6-Deoxy-3-O-Methyl-α-L-glucopyranosyl)oxy]-14-hydroxy-19-oxocard-20(22)-enolide
- Peruvoside (90%)
- (3beta,5beta)-3-[(6-deoxy-3-O-methyl-alpha-L\-glucopyranosyl)oxy]-14-hydroxy-19-oxocard-20(22)-enolide
- PERUVOSIDE FROM THEVETIA NERIIFOLIA
- PERUVOSIDE(RG)
- (3-beta,5-beta)-oxy-19-oxo
- 3-((6-deoxy-3-o-methyl-alpha-l-glucopyranosyl)oxy)-14-hydroxy-19-oxo-card-20
- cannogeninalpha-l-thevetoside
- cannogeninthevetoside
- card-20(22)-enolide,3-((6-deoxy-3-o-methyl-alpha-l-glucopyranosyl)oxy)-14-hydr
- encordin
- peruvosid
- CANNOGENNIN-ALPHA-L-THEVETOSIDE
- [3BETA,5BETA]-3-[6-DEOXY-3-O-METHYL-ALPHA-L-GLUCOPYRANOSYL)OXYL]-14-HYDROXY-19-OXOCARD-20[22]-ENOLIDE
- PERUVOSIDE USP/EP/BP
- (3S,5R,8R,9S,10R,13R,14S,17R)-3-[(2R,3S,4R,5S,6S)-3,5-dihydroxy-4-methoxy-6-methyloxan-2-yl]oxy-14-hydroxy-13-methyl-17-(5-oxo-2H-furan-3-yl)-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthrene-10-carbaldehyde
- Card-20(22)-enolide, 3-[(6-deoxy-3-O-methyl-α-L-glucopyranosyl)oxy]-14-hydroxy-19-oxo-, (3β,5β)-
- 1182-87-2
- C30H44O9
