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THZ1

THZ1 Struktur
1604810-83-4
CAS-Nr.
1604810-83-4
Englisch Name:
THZ1
Synonyma:
THZ1;CS-1233;CDK7 inhibitor;THZ1 free base;THZ1, CDK7 inhibitor;THZ-1;THZ 1;CDK7 INHIBITOR;CDK7 INHIBITOR; THZ-1; THZ 1;THZ1 HY-80013 GTPL8052 SCHEMBL14979765;(E)-N-(3-((5-Chloro-4-(1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)-4-(4-(dimethylamino)but-2-en;(E)-N-(3-((5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)-4-(4-(dimethylamino)but-2-enamido)benzamide
CBNumber:
CB02715672
Summenformel:
C31H28ClN7O2
Molgewicht:
566.05
MOL-Datei:
1604810-83-4.mol
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THZ1 Eigenschaften

Dichte
1.379±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
Löslichkeit
≥28.3 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH
Aggregatzustand
Powder
pka
12.94±0.70(Predicted)

Sicherheit

THZ1 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

THZ1 is a covalent cyclin-dependent kinases 7 (CDK7) inhibitor. It has the ability to target a remote cysteine residue located outside of the canonical kinase domain, providing a means of achieving selectivity for CDK7.

THZ1 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

THZ1 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 105)Lieferanten
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ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795
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 ada@ipurechemical.com China 10326 58
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InvivoChem 		+1-708-310-1919 +1-13798911105
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ShenZhen Trendseen Biological Technology Co.,Ltd. 		13417589054
 trendseenbio@gmail.com China 11681 58
  • (E)-N-(3-((5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)-4-(4-(dimethylamino)but-2-enamido)benzamide THZ1
  • THZ1
  • N-[3-[[5-Chloro-4-(1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]-4-[[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]amino]benzamide
  • (E)-N-(3-((5-Chloro-4-(1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)-4-(4-(dimethylamino)but-2-en
  • (E)-N-(3-((5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)-4-(4-(dimethylamino)but-2-enamido)benzamide
  • THZ-1;THZ 1;CDK7 INHIBITOR
  • THZ1 HY-80013 GTPL8052 SCHEMBL14979765
  • Benzamide, N-[3-[[5-chloro-4-(1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]-4-[[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]amino]-
  • CS-1233
  • THZ1, CDK7 inhibitor
  • CDK7 inhibitor
  • CDK7 INHIBITOR; THZ-1; THZ 1
  • THZ1 free base
  • THZ1 ?N-{4-[5-Chloro-4-(1H-indol-3-yl)-pyrimidin-2-ylamino]-phenyl}-4-(4-dimethylamino-but-2-enoylamino)-benzamide
  • (E)-N-(3-((5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)-4-(4-(dimethylamino)but-2-enamido)benzamide hydrochloride
  • 1604810-83-4
  • 16048-83-4
  • C31H28ClN7O2
  • API
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