Monoclonal Anti-HLA Class I Antigen Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
FITC Monoclonal Anti-Human HLA Class I Antigen may be used for immunochemical analysis of HLA Class I antigens; Studies of HLA-A,B,C expression on embryonic and neoplastic tissues; and/or the purification of HLA-A,B,C antigens.
Allgemeine Beschreibung
Monoclonal Anti-Human HLA Class I Antigen (mouse IgG2a isotype) is derived from the hybridoma produced by the fusion of mouse myeloma cell line NS-1 and splenocytes from BALB/c mice immunized with human tonsil leukocyte membrane preparation. Class I proteins are highly polymorphic. HLA-A, -B, -C are classical class I proteins and are heterodimers. HLA-A consists of a polymorphic transmembrane α heavy chain and an invariant water-soluble light chain.
Biochem/physiol Actions
HLA class I molecules like HLA-A,?-B and ?C help in the presentation of endogenous antigen to CD8+ (cluster of differentiation 8) T cells.
Monoclonal Anti-HLA Class I Antigen Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
