OPN
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- CAS-Nr.
- Englisch Name:
- OPN
- Synonyma:
- OPN;OSTP;SPP1;BOVINE OPN;OSTEOPONTIN;Nephropontin;BOVINE OSTEOPONTIN;BONE SIALOPROTEIN-1;OSTEOPONTIN, BOVINE;OSTEOPONTIN (HUMAN)
- CBNumber:
- CB0332095
- Summenformel:
- Molgewicht:
- 0
- MOL-Datei:
- Mol file
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OPN Eigenschaften
- storage temp.
- -20°C
- Aggregatzustand
- lyophilized powder
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| RIDADR |
UN 3264 8 / PGIII |
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| WGK Germany |
3 |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H290 |
Kann gegenüber Metallen korrosiv sein. |
Korrosiv gegenüber Metallen |
Kategorie 1 |
Warnung |
![GHS hazard pictograms]() src="/GHS05.jpg" width="20" height="20" /> |
P234, P390, P404 |
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| Sicherheit |
| P234 |
Nur im Originalbehälter aufbewahren. |
| P390 |
Verschüttete Mengen aufnehmen, um Materialschäden zu vermeiden. |
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OPN Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT
Procedure (sandwich, competitive & Indirect ELISA)
Allgemeine Beschreibung
The Human OPN ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human OPN in serum, plasma, cell culture supernatants and urine.
Biochem/physiol Actions
Osteopontin (OPN) is a secreted glycoprotein and is assumed to be associated with various cellular processes such as adhesion, migration, and biomineralization in diverse tissues. Osteopontin acts as a ligand to αvβ3 integrin and possibly other receptors. In addition to its involvement in mineralized matrix formation, osteopontin can also function as a cytokine that stimulates the release of IFNγ (interferon γ) and IL-12 (interleukin 12), while inhibiting the production of IL-10. Osteopontin is involved in inflammation and also regulates immunity against infectious diseases. It also co-stimulates T cell proliferation. Osteopontin has proinflammatory functions and is associated with multiple sclerosis. It participates in inflammation in Crohn′s Disease. Osteopontin plays a crucial role in bone remodelling and retards ectopic calcification by inhibiting the formation of hydroxyapatite. OPN is thought to prevent renal stone formation by suppressing nucleation, growth and aggregation of calcium oxalate crystals.
OPN Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
OPN Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 34)Lieferanten
- Anti-Osteopontin, C-Terminal antibody produced in rabbit
- ANTI-OPN-A/B(N-TERMINAL) antibody produced in rabbit
- OPN
- BOVINE OPN
- EARLY T LYMPHOCYTE ACTIVATION PROTEIN-1 (ETA-1)
- BONE SIALOPROTEIN-1
- BOVINE OSTEOPONTIN
- Bone Sialoprotein-1, Early T Lymphocyte Activation Protein-1 (ETA-1), OPN, Secreted Phosphoprotein 1 (Spp1)
- Osteopontin from mouse
- Osteopontin from bovine milk
- SECRETED PHOSPHOPROTEIN 1 (SPP1)
- OSTEOPONTIN, BOVINE
- OSTEOPONTIN
- OSTEOPONTIN (HUMAN)
- OSTEOPONTIN, HUMAN MILK
- Nephropontin
- OSTP
- Mouse Osteopontin ELISA Kit
- SPP1
- Human Osteopontin ELISA Kit
- Recombinant Human SPP1 Protein, His Tag
- Rabbit Anti-Osteopontin antibody
- 多肽抗原
