RSPO1

RSPO1 Struktur
CAS-Nr.
Englisch Name:
RSPO1
Synonyma:
RSPO1;HRspo1;FLJ40906;CRISTIN3;RSPONDIN;R-spondin 1;R-SPONDIN-1 human;Roof plate-specific spondin-1;Recombinant Human RSPO1 Protein, His Tag;Monoclonal Anti-RSPO1 antibody produced in mouse
CBNumber:
CB12912843
Summenformel:
Molgewicht:
0
MOL-Datei:
Mol file

RSPO1 Eigenschaften

storage temp. 
-20°C
Aggregatzustand
lyophilized
Farbe
white

Sicherheit

WGK Germany  3

RSPO1 Chemische Eigenschaften,Einsatz,Produktion Methoden

Allgemeine Beschreibung

R-Spondin-1 (Rspo-1) belongs to the (Rspo) family of Wnt modulators. Currently, the (Rspo) family consists of four structurally related secreted ligands (Rspo 1-4), all containing furin-like and thrombospondin structural domains. Rspo-1 is expressed in certain areas of the developing central nervous system, as well as in adrenal glands, ovary, testis, thyroid, and trachea. Recombinant human R-Spondin-1 is a 26.7kDa protein consisting of 243 amino acid residues. Due to glycosylation, R-Spondin-1 migrates at an apparent molecular weight of approximately 40.0kDa by SDS PAGE analysis under reducing conditions.

Biochem/physiol Actions

Rspo (R-Spondin) can interact with the Frizzled/LRP6 (LDL receptor related protein 6) receptor complex in a manner that stimulates the Wnt/beta-catenin signaling pathway. Disruption of Rspo-1 gene causes recessive syndrome with XX sex reversal, palmoplantar hyperkeratosis and predisposition to squamous cell carcinoma of the skin. Rspo-1 is also associated with radioresistance of tumor cells.

RSPO1 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


RSPO1 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 12)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Sigma-Aldrich 021-61415566 800-8193336
orderCN@merckgroup.com China 51471 80
Wuhan Chemstan Biotechnology Co., Ltd. 027-65317797 15926423062
422450190@qq.com China 10351 58
Gongyishengan Technology (Shenzhen) Co., Ltd. +86-0755-89218110 +86-13480856786
2880189130@qq.com China 919 58
Biolab Reagents 027-65279366 18162686757
products@biolabreagent.com China 9818 58
ACROBiosystems 18514007688
jiaxin.zhao@acrobiosystems.com China 1002 58

  • CRISTIN3
  • FLJ40906
  • Monoclonal Anti-RSPO1 antibody produced in mouse
  • RSPO1
  • R-SPONDIN-1 human
  • HRspo1
  • Roof plate-specific spondin-1
  • RSPONDIN
  • R-spondin 1
  • Recombinant Human RSPO1 Protein, His Tag
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