Protirelin
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- CAS-Nr.
- 24305-27-9
- Bezeichnung:
- Protirelin
- Englisch Name:
- Thyrotropin-releasing hormone
- Synonyma:
- PROTIRELIN;PIN2;TRF;THYROTROPIN RELEASING HORMONE;TRH (Thyrotropin Releasing Hormone);TRH;Prem;TRF1;TRBF1;TERF1
- CBNumber:
- CB1408948
- Summenformel:
- C16H22N6O4
- Molgewicht:
- 362.38
- MOL-Datei:
- 24305-27-9.mol
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Protirelin Eigenschaften
- Schmelzpunkt:
- >143°C (dec.)
- alpha
- -50 (D/25℃) (c=1.5, H2O)-65.5 (D) (c=1.0, H2O)
- Siedepunkt:
- 494°C (rough estimate)
- Dichte
- 1.1675 (rough estimate)
- Brechungsindex
- 1.6000 (estimate)
- storage temp.
- −20°C
- Löslichkeit
- H2O: 10 mg/mL, clear, colorless
- pka
- 13.05±0.20(Predicted)
- Aggregatzustand
- powder
- Farbe
- White to Off-White
- PH
- pH (10g/l, 25℃) : 3.0～4.0
- Merck
- 13,9663
- BRN
- 770238
- Stabilität:
- Hygroscopic
- InChIKey
- ITYONPBTNRIEBA-SRVKXCTJSA-N
- CAS Datenbank
- 24305-27-9
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitsschädlich bei Verschlucken. |
Akute Toxizität oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P305+P351+P338,P337+P313P |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizität (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
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| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen. |
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Protirelin Chemische Eigenschaften,Einsatz,Produktion Methoden
S-Sätze Betriebsanweisung:
S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
Chemische Eigenschaften
White or yellowish-white powder, hygroscopic.
Verwenden
prothyrotropin
Indications
Thyrotropin-releasing hormone, or protirelin, consists
of three amino acids. TRH (Relefact TRH) is used for
tests to distinguish primary from secondary hypothyroidism.
Allgemeine Beschreibung
Thyrotropin releasing hormone (TRH) is a tripeptide hypothalamic regulatory hormone, encoded by the gene mapped to human chromosome 3q13.3-q21. TRH is expressed in a variety of organs including central nervous system (CNS) and gastrointestinal tract.
Nebenwirkungen
The peak TSH response to intravenous TRH occurs at 20 minutes. The mild and transient side effects, which occur only after intravenous TRH, include nausea, a flushing sensation, a desire to micturate, a peculiar taste, and tightness in the chest[1].
Protirelin Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Protirelin Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 281)Lieferanten
24305-27-9(Protirelin)Verwandte Suche:
- synthetictsh-releasinghormone
- THYROTROPIN RELEASING HORMONE ACETATE TE
- PGLU-HIS-PRO AMIDE ACETATE F & D VERSIO
- GLP-HIS-PRO-NH2
- H-PGLU-HIS-PRO-NH2
- L-PYROGLUTAMYL-L-HISTIDYL-L-PROLINAMIDE
- THYROLIBERIN
- THYROTROPIN RELEASING HORMONE 1-2
- THYROTROPIN RELEASING HORMONE 2-3
- THYROTROPIC RELEASING HORMONE
- THYROTROPIN RELEASING HORMONE, HUMAN
- THYROTROPIN RELEASING HORMONE (HUMAN, OVINE, PORCINE, RAT)
- Thyrotropic hormone-releasing hormone
- Thyrotropin-releasing factor (8CI)
- PROTIRELIN PH. EUR.
- (2S)-N-[(2S)-1-[(2S)-2-carbamoylpyrrolidin-1-yl]-3-(3H-imidazol-4-yl)-1-oxo-propan-2-yl]-5-oxo-pyrrolidine-2-carboxamide
- (Pyro)-L-glutamic acid-L-histidine-L-proline-NH2
- Abbott 38579
- L-Prolinamide, 5-oxo-L-prolyl-L-histidyl- (9CI)
- Prem
- Relefact TRH
- Rifotironin
- Stimu TSH
- Synthetic thyrotropin-releasing factor
- Synthetic thyrotropin-releasing hormone
- Thypinone
- Thyrefact
- Thyroid-stimulating hormone-releasing factor
- Thyrotropic hormone-releasing factor
- 4,5-DIAMINO-6-HYDROXY-2-PYRIMIDINETHIOL HEMISULFATE-1,5-HYDRATE
- TRH
- TRH, HUMAN
- TRH (HUMAN, OVINE, PORCINE, RAT)
- THR 1-2
- THR 2-3
- PYROGLU-HIS-PRO AMIDE
- PYROGLU-HIS-PRO NH2
- PYR-HIS-PRO-NH2(TRH)
- PYR-HIS-PRO-NH2
- PGLU-HIS-PRO-NH2
- PGLU-HIS-PRO AMIDE
- 5-oxo-l-prolyl-l-histidyl-l-prolinamid
- fda1725
- lopremone
- (2S)-N-[(2S)-1-[(2S)-2-Carbamoylpyrrolidin-1-yl]-3-(1H-imidazol-2-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide
- GLP-HIS-PRO-NH2: GLP-HP-NH2
- Pyr-HP-NH2
- hTRF1-AS
- Monoclonal Anti-TERF1 antibody produced in mouse
- TRF1
- t-TRF1
- ANTI-TRF (TERF1)(C-TERMINAL) antibody produced in rabbit
- TRBF1
- Anti-Telomeric Repeat Binding Factor 1 antibody produced in rabbit
- NIMA-interacting protein 2
- TERF1
- TTAGGG repeat binding factor 1
- thyroidreleasinghormone
