MBX2546

MBX2546 Struktur
695160-12-4
CAS-Nr.
695160-12-4
Englisch Name:
MBX2546
Synonyma:
MBX2546;Acetamide, N-(3,5-dimethylphenyl)-2-[(2-methyl-5-nitrophenyl)(methylsulfonyl)amino]-
CBNumber:
CB14744550
Summenformel:
C18H21N3O5S
Molgewicht:
391.44
MOL-Datei:
695160-12-4.mol

MBX2546 Eigenschaften

Dichte
1.365±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
pka
12.93±0.70(Predicted)
Aggregatzustand
powder
Farbe
white to beige

Sicherheit

MBX2546 Chemische Eigenschaften,Einsatz,Produktion Methoden

Biochem/physiol Actions

MBX2546 is a non-cytotoxic (CC50 >100 μM; 283T) molecule that inhibits against influenza hemagglutinin- (HA-) mediated viral entry (IC90 = 5.7 μM against HIV/HA(H5) entry in 293T culture vs. IC90 >100 μM, 98.2 μM, and >85 μM against HIV/LASV-GP, HIV/EBOV-GP, HIV/VSV-G, respectively) by targeting group 1 HA-specific conformational epitope in the HA stem loop region. MBX2546 is shown to inhibit influenza A strains A/PR/8/34 (H1N1) and A/Florida/21/2008 (H1N1-H275Ψ) (oseltamivir-resistant strain), A/California/10/2009/H1N1, as well as high pathogenic avian influenza (HPAI) strain A/Hong Kong/H5N1 (IC50 = 0.3, 5.8, 0.55-1.5, and 3.6 μM, respectively), but not A/Texas/12/2007 (H3N2), A/Perth/16/2009 (H3N2), A/Victoria/3/75 (H3N2), A/Panama/2007/99 (H3N2), A/Sydney/05/97 (H3N2), A/California/7/04 (H3N2), A/Wyoming/03/2003 (H3N2), or influenza B strain B/Florida/4/2006 in MDCK cultures.

MBX2546 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


MBX2546 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 4)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000
marketing@targetmol.com United States 19892 58
Sigma-Aldrich 021-61415566 800-8193336
orderCN@merckgroup.com China 51471 80
TargetMol Chemicals Inc. 4008200310
marketing@tsbiochem.com China 23980 58

  • MBX2546
  • Acetamide, N-(3,5-dimethylphenyl)-2-[(2-methyl-5-nitrophenyl)(methylsulfonyl)amino]-
  • 695160-12-4
Copyright 2019 © ChemicalBook. All rights reserved