Anti-Eukaryotic Release Factor 3a, Anti-G1 to S phase transition 1, Anti-GST1, homolog of yeast

CAS-Nr.

Englisch Name:: Anti-Eukaryotic Release Factor 3a, Anti-G1 to S phase transition 1, Anti-GST1, homolog of yeast

Synonyma:: gspt1;zgc:91975;Anti-GST1;Anti-GTH4;Anti-ETF3A;Anti-eRF3a;Anti-GSTM2;Anti-GST1, homolog of yeast;GTP-binding protein GST1-HS;Anti-G1 to S phase transition 1

CBNumber:: CB22100689

Summenformel:

Molgewicht:: 0

MOL-Datei:: Mol file

Request For Quotation

Eigenschaften Sicherheit Verwendungswort Produktionsfirma 3

Anti-Eukaryotic Release Factor 3a, Anti-G1 to S phase transition 1, Anti-GST1, homolog of yeast Eigenschaften

storage temp.: -20°C

Aggregatzustand: buffered aqueous solution

Sicherheit

Risiko- und Sicherheitserklärung
Gefahreninformationscode (GHS)

Bildanzeige (GHS)

Alarmwort

Warnung

Gefahrenhinweise

Code	Gefahrenhinweise	Gefahrenklasse	Abteilung	Alarmwort	Symbol	P-Code
H315	Verursacht Hautreizungen.	Hautreizung	Kategorie 2	Warnung	src="/GHS07.jpg" width="20" height="20" />	P264, P280, P302+P352, P321,P332+P313, P362
H319	Verursacht schwere Augenreizung.	Schwere Augenreizung	Kategorie 2	Warnung	src="/GHS07.jpg" width="20" height="20" />	P264, P280, P305+P351+P338,P337+P313P

Sicherheit

P305+P351+P338

BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen.

Anti-Eukaryotic Release Factor 3a, Anti-G1 to S phase transition 1, Anti-GST1, homolog of yeast Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Anti-eRF3a/GSPT1 (N-terminal) antibody produced in rabbit is suitable for immunoprecipitation at a concentration of 2-5μL using HeLa cell lysates and western blotting at a dilution of 1:500-1:1,000 using HeLa cell lysates.

Allgemeine Beschreibung

Eukaryotic release factor 3 a (eRF3a) is encoded by the gene G1 to S phase transition 1 (GSPT1) in humans. The eRF3a/GSPT1 exon 1 is a translation termination protein characterized with a tri-nucleotide GGC repeat coding for a polyglycine expansion in the amino-terminal end.

Biochem/physiol Actions

Eukaryotic release factor 3a (eRF3a) is a translation termination protein that is encoded by G1 to S phase transition 1 gene (GSPT1) in humans. The eRF3a/GSPT1 exon 1 contains a tri-nucleotide GGC repeat coding for a polyglycine expansion in the N-terminal of the protein. It is associated with protein translation as a regulator of apoptosis signal-regulating kinase 1 (ASK1). GSPT1 interacts with ASK1 and enhances ASK1-induced apoptotic activity by activating caspase-3. It plays a novel role in the regulation of ASK1-mediated apoptosis. GSPT1 is found to be up-regulated in various human cancers and is considered as a potential proto-oncogene.

Anti-Eukaryotic Release Factor 3a, Anti-G1 to S phase transition 1, Anti-GST1, homolog of yeast Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Anti-Eukaryotic Release Factor 3a, Anti-G1 to S phase transition 1, Anti-GST1, homolog of yeast Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 3)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51471	80

Anti-eRF3a/GSPT1 (N-terminal) antibody produced in rabbit
Anti-Eukaryotic Release Factor 3a, Anti-G1 to S phase transition 1, Anti-GST1, homolog of yeast
Anti-eRF3a/GSPT1 antibody produced in rabbit
Anti-eRF3a
Anti-ETF3A
Anti-GSPT1 antibody produced in rabbit
Anti-GST1
gspt1
zgc:91975
Anti-Eukaryotic Release Factor 3a
Anti-G1 to S phase transition 1
Anti-GST1, homolog of yeast
G1 to S phase transition protein 1 homolog
GTP-binding protein GST1-HS
Anti-GSTM1/GSTM2 antibody produced in goat
Anti-GSTM2
Anti-GTH4