ADRENIC ACID

ADRENIC ACID Struktur
28874-58-0
CAS-Nr.
28874-58-0
Englisch Name:
ADRENIC ACID
Synonyma:
ADRENIC ACID;DOCOSATETRAENOIC ACID;Adrenic Acid (22:4, n-6);Ethyl Acetate Impurity 104;Adrenic Acid (Solution in ethanol);Adrenic acid(cis-7,10,13,16)(C22:4);7Z,10Z,13Z,16Z-DOCOSATETRAENOIC ACID;DOCOSA-7Z,10Z,13Z,16Z-TETRAENOIC ACID;DOCOSA-7Z,10Z,13Z,16Z-PENTAENOIC ACID;CIS-7,10,13,16-DOCOSA-TETRAENOIC ACID
CBNumber:
CB2456229
Summenformel:
C22H36O2
Molgewicht:
332.52
MOL-Datei:
28874-58-0.mol

ADRENIC ACID Eigenschaften

Siedepunkt:
161-164.5 °C(Press: 0.07 Torr)
Dichte
0.9220 g/cm3
storage temp. 
−20°C
Löslichkeit
Chloroform (Sparingly), Methanol (Slightly)
pka
4.76±0.10(Predicted)
Aggregatzustand
Oil
Farbe
Colourless
Stabilität:
Light Sensitive
Sicherheit
  • Risiko- und Sicherheitserklärung
  • Gefahreninformationscode (GHS)
WGK Germany  3
Bildanzeige (GHS) GHS hazard pictogramsGHS hazard pictograms
Alarmwort Achtung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H225 Flüssigkeit und Dampf leicht entzündbar. Entzündbare Flüssigkeiten Kategorie 2 Achtung GHS hazard pictogramssrc="/GHS02.jpg" width="20" height="20" /> P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
Sicherheit
P210 Von Hitze, heißen Oberflächen, Funken, offenen Flammen und anderen Zündquellenarten fernhalten. Nicht rauchen.
P233 Behälter dicht verschlossen halten.
P240 Behälter und zu befüllende Anlage erden.
P241 Explosionsgeschützte [elektrische/Lüftungs-/ Beleuchtungs-/...] Geräte verwenden.
P242 Nur funkenfreies Werkzeug verwenden.
P243 Maßnahmen gegen elektrostatische Entladungen treffen.
P264 Nach Gebrauch gründlich waschen.
P264 Nach Gebrauch gründlich waschen.
P280 Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.
P303+P361+P353 BEI BERÜHRUNG MIT DER HAUT (oder dem Haar): Alle kontaminierten Kleidungsstücke sofort ausziehen. Haut mit Wasser abwaschen oder duschen.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen.
P337+P313 Bei anhaltender Augenreizung: Ärztlichen Rat einholen/ärztliche Hilfe hinzuziehen.
P370+P378 Bei Brand: zum Löschen verwenden.
P403+P235 An einem gut belüfteten Ort aufbewahren. Kühl halten.

ADRENIC ACID Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Adrenic acid is a naturally occurring polyunsaturated fatty acid (PUFA) formed through a 2-carbon chain elongation of arachidonic acid. It is present in the adrenal glands, brain, testis, and kidney. Although there is trace metabolism of adrenic acid in the forebrain, the renal medulla is the only tissue which readily metabolizes the acid through cyclooxygenase activity. The primary metabolite of adrenic acid in the rabbit kidney is 1a,1b-dihomo prostaglandin E2.

Chemische Eigenschaften

Docosa tetra enoic acid designates any straight chain 22:4 fatty acid.
One isomer is of particular interest :
all-cis-7,10,13,16-docosa tetra enoic acid is an ω-6 fatty acid with the trivial name adrenic acid. This is a naturally occurring polyunsaturated fatty acid formed through a 2-carbon chain elongation of arachidonic acid. It is one of the most abundant fatty acids in the early human brain.

Verwenden

Adrenic acid is considered a sort of storage form of arachidnoic acid because it can be retro-converted into arachidonic acid by enzymes. Arachidonic acid is relatively abundant especially in the phospholipids that are found in cellular membranes, and it is precursor for many hormone-like signaling molecules, e.g. prostaglandins and leukotrienes. It shall be liberated from the phospholipids by phospholipase enzymes before it can be converted into these signaling molecules. Omnivorous humans also consume small amounts of arachidonic acid with the diet, since arachidonic acid is found in small amounts in all animal products. Arachidonic acid is not found in higher plants. Arachidonic acid serves many important functions in the body, e.g. as a structural element in membrane phospholipids, and as precursor for signalling.

Enzyminhibitor

This long-chain, unsaturated fatty acid (FWfree-acid = 332.53 g/mol; CAS 28874-58-0), also known as adrenic acid and (7Z,10Z,13Z,16Z)- docosatetraenoic acid, inhibits arachidonyl-CoA synthetase, orarachidonate:CoA ligase and prostaglandin biosynthesis.

ADRENIC ACID Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


ADRENIC ACID Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 63)Lieferanten
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28874-58-0()Verwandte Suche:


  • CIS-7,10,13,16,19-DOCOSA-TETRAENOIC ACID
  • CIS-7,10,13,16-DOCOSA-TETRAENOIC ACID
  • DOCOSATETRAENOIC ACID
  • DOCOSA-7Z,10Z,13Z,16Z-PENTAENOIC ACID
  • DOCOSA-7Z,10Z,13Z,16Z-TETRAENOIC ACID
  • cis-7,10,13,16-Docosatetraenoic acid, C22:4n6
  • 7Z,10Z,13Z,16Z-DOCOSATETRAENOIC ACID
  • ADRENIC ACID
  • (All-Z)-7,10,13,16-docosatetraenoic acid
  • 7,10,13,16-Docosatetraenoic acid, (all-Z)-
  • 7,10,13,16-Docosatetraenoic acid (all-cis)
  • Adrenic Acid (22:4, n-6)
  • (7Z,10Z,13Z,16Z)-Docosa-7,10,13,16-tetraenoic acid
  • Adrenic Acid (Solution in ethanol)
  • 7,10,13,16-Docosatetraenoic acid, (7Z,10Z,13Z,16Z)-
  • Adrenic acid(cis-7,10,13,16)(C22:4)
  • all-cis-docosa-7,10,13,16-tetraenoicaci
  • Endogenous Metabolite,vascular,Inhibitor,fatty,Adrenic Acid,polyunsaturated,inflammation,inhibit
  • Ethyl Acetate Impurity 104
  • 28874-58-0
  • C5H11CHCHCH24CH24COOH
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  • Fatty Acids
  • Omega 6 fatty acids and derivatives
  • Polyunsaturated
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  • Unsaturated fatty acids and derivatives
  • DJ - DZUnsaturated fatty acids and derivatives
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  • Omega 6 fatty acids and derivatives
  • Polyunsaturated
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