InSolution IKK-2 Inhibitor IV - Calbiochem

InSolution IKK-2 Inhibitor IV - Calbiochem Chemische Eigenschaften,Einsatz,Produktion Methoden

Allgemeine Beschreibung

IKK-2 Inhibitor IV (Cat. No. 401481) supplied in DMSO. A cell-permeable and potent inhibitor of IKK-2 (IC₅₀ = 18 nM) that exhibits selectivity over IKK-1, JNK, and p38 MAPK. Inhibits TNF-α production in human monocytes (IC₅₀ in the range of 0.15-2.5 μM) and blocks IL-8 and IL-6 production by synovial fibroblasts (IC₅₀ = 100 nM). Shown to reduce paw oedema in rat arthritis model (~100% inhibition at a dose of 30 mg/kg).

Biochem/physiol Actions

Cell permeable: yes

InSolution IKK-2 Inhibitor IV - Calbiochem Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

InSolution IKK-2 Inhibitor IV - Calbiochem Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51471	80

---

• InSolution IKK-2 Inhibitor IV - Calbiochem