Eurycomanone

Eurycomanone Struktur
84633-29-4
CAS-Nr.
84633-29-4
Englisch Name:
Eurycomanone
Synonyma:
NSC 339187;eurysanone;EURYCOMANONE;pasakbumin-a;tonkat ali extract;Eurycoma longifolia;Eurycomanone (~90%);Broad tassel ketone;EurycomalongifoliaJack;Extract of Orion nigrum
CBNumber:
CB3189926
Summenformel:
C20H24O9
Molgewicht:
408.4
MOL-Datei:
84633-29-4.mol

Eurycomanone Eigenschaften

Schmelzpunkt:
273-285℃ (methanol ethyl ether )
Siedepunkt:
669.5±55.0 °C(Predicted)
Dichte
1.63±0.1 g/cm3(Predicted)
storage temp. 
-20°C Freezer
Löslichkeit
DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)
Aggregatzustand
Solid
pka
11.29±0.70(Predicted)
Farbe
Off-White to Pale Beige
InChIKey
RRXCMOJNEHOTBC-OHYAWSEYNA-N
SMILES
[C@]123CO[C@@]4(O)[C@H](O)C(=C)[C@]1(O)[C@@H](O)C(=O)O[C@]2([H])C[C@@]1([H])C(C)=CC(=O)[C@@H](O)[C@]1(C)[C@]34[H].O.O |&1:0,3,5,9,11,16,19,26,28,30,r|

Sicherheit

Eurycomanone Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Eurycomanone is known as a cytotoxic compound found in Eurycoma Longifolia Jack. Previous studies had noted its cytotoxic effects against various cancer cell lines. More recent research demonstrated the ability of Eurycomanone to suppress the expression of lung cancer cell tumor markers, prohibitin, annexin 1 and endoplasmic reticulum protein 28. Eurycomanone was shown to also exerts the ability to induce apoptosis through the up-regulation of p53 in human cervical carcinoma cells.

Definition

ChEBI: A quassinoid isolated from Eurycoma longifolia and has been shown to exhibit antineoplastic and antimalarial activties.

Manufacturing Process

The extraction and purification process of eurycomanone in a kind of Tongkat Ali plant:
The preparation of the first medicinal extract: Tongkat Ali tree root meal is gone out eurycomanone with solvent extraction, extracting solution, concentrating under reduced pressure obtains Tongkat Ali medicinal extract.
Second degreasing: by Tongkat Ali medicinal extract with petroleum ether extraction, leaves standstill, layering. The low-pole compositions include removing fat-soluble pigment.
3rd extracting and separating: the medicinal extract after petroleum ether degreasing with extraction into ethyl acetate, obtain the ethyl acetate solution of eurycomanone.
4th pillar layer separation: the ethyl acetate solution of eurycomanone is separated with silica gel column chromatography, obtaining the elutriant containing eurycomanone.
5th decolouring: the composition containing eurycomanone is activated carbon decolorizing.
6th concentrates and crystallization: the destainer concentrates under reduced pressure of eurycomanone, and crystallization obtains the crude product eurycomanone.
7th purifying: add sherwood oil in crude product eurycomanone, then drip a little ethyl acetate, by the impurity pigment washing removing on crystallisate, obtain the xln of white.
8th filters, dry: by the vacuum-drying of eurycomanone xln.

Eurycomanone Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Eurycomanone Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 147)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Chengdu Biopurify Phytochemicals Ltd.
+8618080483897
sales@biopurify.com China 3772 58
Wuhan senwayer century chemical Co.,Ltd
+undefined-27-86652399 +undefined13627115097
market02@senwayer.com China 905 58
Henan Fengda Chemical Co., Ltd
+86-371-86557731 +86-13613820652
info@fdachem.com China 20293 58
Shanghai Daken Advanced Materials Co.,Ltd
+86-371-66670886
info@dakenam.com China 18629 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512
info@tianfuchem.com China 21667 55
Hangzhou FandaChem Co.,Ltd.
008657128800458; +8615858145714
fandachem@gmail.com China 9355 55
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795
ivan@atkchemical.com China 32836 60
career henan chemical co
+86-0371-86658258 +8613203830695
sales@coreychem.com China 29888 58
Chengdu GLP biotechnology Co Ltd
028-87075086 13350802083
scglp@glp-china.com CHINA 1824 58
Hubei Jusheng Technology Co.,Ltd.
18871490254
linda@hubeijusheng.com CHINA 28180 58

84633-29-4()Verwandte Suche:


  • EURYCOMANONE
  • 11,2o-epoxy-1,11,12,14,15-pentahydroxy-13(21)-diene-(1-picrasa-16-dione
  • 11-beta,12-alpha,15-beta)-betdihydrate
  • pasakbumin-a
  • 11β,20-Epoxy-1β,11,12α,14,15β-pentahydroxypicrasa-3,13(21)-diene-2,16-dione
  • NSC 339187
  • (1beta,8xi,11beta,12alpha,15beta)-1,11,12,14,15-pentahydroxy-11,20-epoxypicrasa-3,13(21)-diene-2,16-dione
  • Eurycoma longifolia
  • Eurycomanone, 98%, from Eurycoma longifolia
  • Extract of Orion nigrum
  • EurycomalongifoliaJack
  • Eurycomanone (Synonyms: Pasakbumin A)
  • Picrasa-3,13(21)-diene-2,16-dione,11,20-epoxy-1,11,12,14,15-pentahydroxy-, (1b,11b,12a,15b)-
  • Picrasa-3,13(21)-diene-2,16-dione, 11,20-epoxy-1,11,12,14,15-pentahydroxy-, (1β,11β,12α,15β)-
  • Extract of amaryllis asiatica l
  • Eurycomanone (~90%)
  • Eurycomanone (Pasakbumin A)
  • tonkat ali extract
  • Broad tassel ketone
  • eurysanone
  • Eurycomanone/Tongkat Ali Extract
  • Eurycoma longifolia 100:1
  • (1R,2R,3aR,3a1R,4R,6aR,7aS,11S,11aS,11bR)-1,2,3a,4,11-Pentahydroxy-8,11a-dimethyl-3-methylene-1,2,3,3a,4,7,7a,11,11a,11b-decahydro-5H-1,3a1-(epoxymethano)dibenzo[de,g]chromene-5,10(6aH)-dione
  • 84633-29-4
  • Apoptosis, Aromatics, Pharmaceuticals, Intermediates & Fine Chemicals
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