3,4-Dihydro-8-hydroxy-3,4,5-trimethyl-6H-6-oxo-benzo(c)pyran-7-carbonsäure Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R23/24/25:Giftig beim Einatmen, Verschlucken und Berührung mit der Haut.
R40:Verdacht auf krebserzeugende Wirkung.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
S22:Staub nicht einatmen.
S7/9:Behälter dicht geschlossen an einem gut gelüfteten Ort aufbewahren.
Chemische Eigenschaften
yellow crystalline powder or flakes
Verwenden
Citrinin is a quinonemethine mycotoxin produced by diverse fungi including Aspergillus and Penicillium. Citrinin has been extensively investigate, and is a potent nephrotoxin with hepatoxic and teratogenic activity. Citrinin is the causative agent of Balkan nephropathy and yellow rice fever in humans. At the molecular level, citrinin exhibits a range of effects including free radical damage to DNA and disruption of mitochondrial membrane-bound enzymic activities and structural integrity. Specifically, citrinin is an inhibitor of NADH dehydrogenase in the mitochondrial electron transport chain and this action is responsible for recent reports of citrinin's apoptotic activity.
Allgemeine Beschreibung
Citrinin is a hepato-nephrotoxic mycotoxin. It can be produced by several filamentous fungi genera of
Monauscus,
Aspergillus, and
Penicillium, which is commonly found as a contaminant in stored grains, foods, feedstuffs and also in biological fluids.
mögliche Exposition
Specific uses for antimycin A were
not found, however, antimycin A1, and antimycin A3 are
reported to be antibiotic substances produced by streptomyces
for use as a fungicide, possible insecticide and miticide.
Registered as a pesticide in the U.S.
Versand/Shipping
UN2811 Toxic solids, organic, n.o.s., Hazard
Class: 6.1; Labels: 6.1-Poisonous materials, Technical
Name Required.
3,4-Dihydro-8-hydroxy-3,4,5-trimethyl-6H-6-oxo-benzo(c)pyran-7-carbonsäure Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
