ANTI-TSG101

ANTI-TSG101 Struktur
CAS-Nr.
Englisch Name:
ANTI-TSG101
Synonyma:
ANTI-TSG101;ANTI-TUMOR SUSPECTIBILITY GENE 101;Anti-ESCRT-I complex subunit TSG101;Anti-Tumor susceptibility gene 101 protein;Anti-TSG101 antibody produced in rabbit
CBNumber:
CB3824375
Summenformel:
Molgewicht:
0
MOL-Datei:
Mol file

ANTI-TSG101 Eigenschaften

storage temp. 
-20°C
Aggregatzustand
buffered aqueous solution

Sicherheit

ANTI-TSG101 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Anti-TSG101 antibody produced in rabbit has been used in western blot analysis.

Allgemeine Beschreibung

Tumor susceptibility 101 (TSG101) is encoded by the gene mapped to human chromosome 11p15.1–15.2. The encoded protein is a member of catalytically inactive ubiquitin E2 variant (UEV) family. Tsg101 is characterized with an ubiquitin E2 variant (UEV) domain in its N-terminal end involved in HIV-1 budding and the vacuolar protein sorting (VPS) pathway.

Biochem/physiol Actions

Tumor susceptibility gene 101 is a human gene that encodes for a cellular protein. It is involed in infection of various papillomaviruses (PVs), and is also responsible for the trafficking of human papillomaviruses (HPV) through the ESCRT machinery and multi-vesicular bodies (MVBs), which forms a part of virus entry. The expression of this gene is related with the TNM stage and metastasis of HCC (hepatocellular carcinoma). It is also found to be expressed in breast cancer cells. Inactivation of this gene in breast cancer cells results in apoptosis and prevents proliferation. The gene might be involved in the control of the MAPK/ERK (mitogen-activated protein kinases/extracellular signal-regulated kinases) signaling pathway in breast cancer.

ANTI-TSG101 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


ANTI-TSG101 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 4)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Sigma-Aldrich 021-61415566 800-8193336
orderCN@merckgroup.com China 51471 80
Shanghai guandao biology engineering co., ltd 18818239863 18818239863
3171921642@qq.com China 8884 58

  • ANTI-TSG101
  • ANTI-TUMOR SUSPECTIBILITY GENE 101
  • Anti-TSG101 antibody produced in rabbit
  • Anti-ESCRT-I complex subunit TSG101
  • Anti-Tumor susceptibility gene 101 protein
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