Rpaf-ah
            
            
            
            
                
                    
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                                    - CAS-Nr.
 
                                    - 208576-22-1
 
                                 
                                
                                
                                    - Englisch Name:
 
                                    - Rpaf-ah
 
                                 
                                
                                    - Synonyma:
 
                                    - Pafase;Rpaf-ah;Epafipase;PAF-AH human;PAF 2-acylhydrolase;Paf acetylhydrolase;Epafipase [usan:inn];LDL-associated phospholipase A2;Deacetylase, 1-alkyl-2-acetyllecithin (human);2-acetyl-1-alkylglycerophosphocholine esterase
 
                                 
                                
                                    - CBNumber:
 
                                    - CB42493219
 
                                 
                                
                                    - Summenformel:
 
                                    
                                 
                                
                                    - Molgewicht:
 
                                    - 0
 
                                 
                                
                                    - MOL-Datei:
 
                                    - Mol file
 
                                 
                             
                            
                             
                            
                                 
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                Rpaf-ah Eigenschaften
                
                
                    
                    
                        - storage temp. 
 
                        - -20°C
 
                    
                    
                    
                        - Aggregatzustand
 
                        - lyophilized
 
                    
                    
                    
                        - Farbe
 
                        - white
 
                    
                    
                    
                        - Biologische Quelle
 
                        - human
 
                    
                    
                 
                
                
             
            
                
                
                
                
                    
                    
                    Rpaf-ah  Chemische Eigenschaften,Einsatz,Produktion Methoden
                    
                    
                    Verwenden
                    Antiallergenic;
antiasthmatic (PAF antagonist [PAF acetylhydrolasemphor.].
                    
                    
                    Allgemeine Beschreibung
                    Recombinant PAF-AH is a 420 amino acid glycoprotein which migrates with an apparent molecular mass of 47-55kDa by SDS-PAGE analysis.
                    
                    
                    Biochem/physiol Actions
                    Platelet Activating Factor (PAF) is a biologically active phospholipid, which exerts primarily proinflammatory activities by specifically signaling through G-protein-coupled receptors on platelets, neutrophils, and monocytes. Platelet activating factor acetylhydrolase (PAF-AH) is a secreted protein that mediates PAF activity by specifically catalyzing hydrolysis of the "sn2" ester bond, resulting in the conversion of PAF to the biologically inactive lyso-PAF. PAF-AH can also interact with LDL (low density lipoprotein) particles to induce the hydrolysis of LDL associated, oxidized phospholipids, generating lysophosphatidylcholine (lyso-PC) and other lysophospholipids. High levels of PAF-AH in plasma can be an indication of resistant hypertension. Polymorphism in PAF-AH gene at A379V might be linked with ischemic stroke susceptibility.
                    
                    
Rpaf-ah Upstream-Materialien And Downstream Produkte
                    Upstream-Materialien
                    
                    Downstream Produkte
                    
                    
                 
                
                
                
                    
                    
                    Rpaf-ah Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
                    
                        Global( 7)Lieferanten     
                        
                     
                    
                    
                    
                 
                
                
                
                
                
                    
                    
                    
                        
                        - 2-Acetyl-1-alkyl-sn-glycero-3-phosphocholine deacetylase-(6-400)-peptide (human)
 
                        
                        - Deacetylase, 1-alkyl-2-acetyllecithin (human)
 
                        
                        - Epafipase
 
                        
                        - Epafipase [usan:inn]
 
                        
                        - Paf acetylhydrolase
 
                        
                        - Pafase
 
                        
                        - Rpaf-ah
 
                        
                        - 2-acetyl-1-alkylglycerophosphocholine esterase
 
                        
                        - LDL-associated phospholipase A2
 
                        
                        - PAF 2-acylhydrolase
 
                        
                        - PAF-AH human
 
                        
                        - 208576-22-1