Dipyrithion

Bispyrithione Struktur
3696-28-4
CAS-Nr.
3696-28-4
Bezeichnung:
Dipyrithion
Englisch Name:
Bispyrithione
Synonyma:
OMDS;osy20;omadineds;NSC 84740;NSC 677437;NSC 241716;ipyrithione;dipyrithione;BISPYRITHIONE;omadinedisulfide
CBNumber:
CB4500917
Summenformel:
C10H8N2O2S2
Molgewicht:
252.31
MOL-Datei:
3696-28-4.mol

Dipyrithion Eigenschaften

Schmelzpunkt:
200.5°C (rough estimate)
Siedepunkt:
582.8±25.0 °C(Predicted)
Dichte
1.4423 (rough estimate)
Brechungsindex
1.5650 (estimate)
Löslichkeit
Methanol (Slightly), Water (Slightly, Heated, Sonicated)
pka
-0.77±0.10(Predicted)
Aggregatzustand
solid
Farbe
Gray or off-white paste
PH
5.0-7.0(25°C,1%soln.)
Stabilität:
Hygroscopic
EPA chemische Informationen
Dipyrithione (3696-28-4)
Sicherheit
  • Risiko- und Sicherheitserklärung
  • Gefahreninformationscode (GHS)
HS Code  2933399990
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H302 Gesundheitsschädlich bei Verschlucken. Akute Toxizität oral Kategorie 4 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P270, P301+P312, P330, P501
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizität (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" />
Sicherheit
P261 Einatmen von Staub vermeiden.
P280 Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.
P301+P312 BEI VERSCHLUCKEN: Bei Unwohlsein GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen.
P302+P352 BEI BERÜHRUNG MIT DER HAUT: Mit viel Wasser/... (Hersteller kann, falls zweckmäßig, ein Reinigungsmittel angeben oder, wenn Wasser eindeutig ungeeignet ist, ein alternatives Mittel empfehlen) waschen.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen.

Dipyrithion Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Bispyrithione is a pyrithione derivate used as bactericide and fungicide. The drug was marketed under the name Crimanex in the form of shampoo for the treatment of dandruff, however it is no longer available on the manufacturer website (Drossa Pharm . It is currently used as a pesticide.

Chemische Eigenschaften

beige to slightly grey powder and chunks

Verwenden

Bispyrithione can be used as an antibacterial; antifungal.

Application

Bispyrithione is a new antidandruff agent behind zinc pyrithione. It has similar chemical structure to zinc pyrithione, thus performs the same bactericidal property, with unique bactericidal actions, especially to mycetes, mild fungus and microzymes. It also can effectively disinfect oval bacil, candia albicans and other mycetes, while normal antimicrobials can't. It is not sensitive to metal ion and dissolves in water more easily than zinc pyrithione, which improves the compatibility and leads to best bactericidal effect. In 2-in-1 shampoo, it doesn't affect the pearly effect but enhance color stability.

Definition

ChEBI: Dipyrithione is a pyridinium ion.

Synthese

1, drop into successively the 600g2-chloropyridine in the 5000ml four-hole boiling flask, 100g maleic and acid anhydrides, 600g hydrogen peroxide (35%) are opened to stir and are warmed up to 60 ℃ of successive reactions 12 hours, make 2-chloropyridine-N-oxide water solution.
2, the 2-chloropyridine that uses the 4000g2-methyl chloride to divide four extractions to make-N-oxide water solution merges extraction phase, and condensing crystal makes sterling 2-chloropyridine-N-oxide compound.
3, the 2-chloropyridine that purification is obtained-N-oxide compound, 430g sodium sulphite, the 2000g high purity water, drop into successively in the 5000ml four-hole boiling flask, open and stir, be warming up to 70 ℃, along with the carrying out of reaction added a part of yellow soda ash in good time, the PH of adjustment system is stabilized in 9~10, and reaction finishes 70 ℃ of insulations 2 hours, and insulation finishes to cool.Make the pyrithione sodium water solution.
4, use an amount of dilute sulphuric acid to adjust the PH to 2 of pyrithione sodium water solution system, separate out a large amount of white crystals.Filtrated stock cleans solid, namely gets pyrithione.
5, the pyrithione that the reaction of upper step is obtained, the 1000g ultrapure water drops in the plastic cup, the unlatching dispersed with stirring is even, then slowly splash into 220g hydrogen peroxide (35%), reaction is 1 hour about 50 ℃, make finished product Bispyrithione 497g (99.72%, five step of content overall yield of reaction: 74.6%).

Dipyrithion Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Dipyrithion Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 106)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
WUXI HONOR SHINE CHEMICAL CO.,LTD
0510-83593312 +8613665125081
sales@honorshinechem.com China 61 58
Wuhan ShuEr Biology Technology Co.,Ltd
+86-15629032529
excellentsuppliers@shuerbio.com China 897 58
Henan Bao Enluo International TradeCo.,LTD
+86-17331933971 +86-17331933971
deasea125996@gmail.com China 2503 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512
info@tianfuchem.com China 21691 55
Shenzhen Nexconn Pharmatechs Ltd
+86-755-89396905 +86-15013857715
admin@nexconn.com China 10248 58
Hubei Jusheng Technology Co.,Ltd.
18871490254
linda@hubeijusheng.com CHINA 28180 58
Shandong chuangyingchemical Co., Ltd.
18853181302
sale@chuangyingchem.com CHINA 5909 58
Hebei shuoxi biotechnology co. LTD
+8613081092107
CHINA 968 58
Hebei Binshare New Material Co. Ltd
+8618633865755
china01@hbbinshare.com CHINA 969 58
Hefei TNJ Chemical Industry Co.,Ltd.
0551-65418671
sales@tnjchem.com China 34572 58

3696-28-4(Dipyrithion)Verwandte Suche:


  • BISPYRITHIONE
  • OMDS
  • Pyrithione disulfide
  • Pyrion disulfide
  • omadinedisulfide
  • omadineds
  • osy20
  • pyridine,2,2’-dithiobis-,1,1’-dioxide
  • pyridine,2,2’-dithiodi-,1,1’-dioxide
  • dipyrithione
  • NSC 84740
  • NSC 677437
  • NSC 241716
  • Di-2-pyridyl disulfide N,N'-dioxide
  • 2,2'-DITHIOBIS(PYRIDINE-N-OXIDE), 97
  • 2,2’-Dithiobis(pyridine-1-oxide)
  • 2,2’-dithiodipyridine-1,1’-dioxide
  • ipyrithione
  • 2,2'-DITHIOBIS(PYRIDINE-N-OXIDE)
  • 2,2'-dithiobis(pyridine-n-oxide), 97
  • 2,2'-Dithiobis(pyridine-N-oxide)
  • 3696-28-4
  • C10H8N2O2S2
  • Antibacterial agent
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