LEVCROMAKALIM

94535-50-9

CAS-Nr.: 94535-50-9

Englisch Name:: LEVCROMAKALIM

Synonyma:: brl38227;lemakalim;Brn 3622889;levcromakelim;LEVCROMAKALIM;LevkroMakaliM;(3s-trans)-yrrolidinyl);Potassium Channel,KcsA,Inhibitor,inhibit,BRL38227,BRL-38227,Levcromakalim;(3β,4α)-3-Hydroxy-2,2-dimethyl-4-(2-oxopyrrolidin-1-yl)chroman-6-carbonitrile;(3S,4R)-3-hydroxy-2,2-dimethyl-4-(2-oxopyrrolidin-1-yl)chroman-6-carbonitrile

CBNumber:: CB5104507

Summenformel:: C16H18N2O3

Molgewicht:: 286.33

MOL-Datei:: 94535-50-9.mol

Request For Quotation

Eigenschaften Sicherheit Verwendungswort Produktionsfirma 53

LEVCROMAKALIM Eigenschaften

Schmelzpunkt:: 242-244°

alpha: D26 -52.2° (c = 1 in chloroform)

Siedepunkt:: 482.3±45.0 °C(Predicted)

Dichte: 1.31±0.1 g/cm3(Predicted)

storage temp.: Store at RT

Löslichkeit: DMSO: ≤10 mM, soluble

pka: 13.18±0.60(Predicted)

Aggregatzustand: solid

Farbe: White to off-white

Sicherheit

S-Sätze:	22-24/25
WGK Germany	3
RTECS-Nr.	DJ2177500

LEVCROMAKALIM Chemische Eigenschaften,Einsatz,Produktion Methoden

S-Sätze Betriebsanweisung:

S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.

Verwenden

Levcromakalim is a potassium channel activator and vasorelaxant used in the management of hypertension in diabetes mellitus.

Biologische Aktivität

Active enantiomer of the prototypical K ATP channel opener cromakalim (trans-3,4-dihydro-3-hydroxy-2,2-dimethyl-4-(2-oxo-1-pyrrolidinyl)-2H-1-benzopyran-6-carbonitrile ). Hypotensive and airways relaxant. IC 50 = 490 nM in guinea pig trachea.

LEVCROMAKALIM Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

LEVCROMAKALIM Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 53)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Hangzhou FandaChem Co.,Ltd.	008657128800458; +8615858145714	fandachem@gmail.com	China	9287	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32836	60
Changzhou PBpharmaceutical R&D Co.,Ltd	0519-83990708	info@pbpharm.com	CHINA	498	58
TopScience Biochemical	00852-68527855	info@itopbiochem.com	China Hong Kong	902	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	sales@molcore.com	China	49739	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	52927	58
3B Pharmachem (Wuhan) International Co.,Ltd.	821-50328103-801 18930552037	3bsc@sina.com	China	15848	69
MedChemexpress LLC	021-58955995	sales@medchemexpress.cn	United States	4863	58
EMMX Biotechnology LLC	888-539-0666	info@emmx.com	United States	8449	60
Changzhou PBpharmaceutical R&D Co.,Ltd	0519-83990708	lxy2046@yeah.net	China	476	55

94535-50-9()Verwandte Suche:

1-Benzyl-3-pyrrolidon 1-(3-Hydroxypropyl)pyrrolidin-2-on

(3S,4R)-3,4-DIHYDRO-3-HYDROXY-2,2-DIMETHYL-4-(2-OXO-1-PYRROLIDINYL)-2H-1-BENZOPYRAN-6-CARBONITRILE
(3s-trans)-yrrolidinyl)
LEVCROMAKALIM
2h-1-benzopyran-6-carbonitrile,3,4-dihydro-3-hydroxy-2,2-dimethyl-4-(2-oxo-1-p
brl38227
lemakalim
levcromakelim
(3S,4R)-3β-Hydroxy-4-(2-oxopyrrolizino)-2,2-dimethyl-3,4-dihydro-6-cyano-2H-1-benzopyran
(3β,4α)-3,4-Dihydro-3-hydroxy-2,2-dimethyl-4-(2-oxopyrrolidin-1-yl)-2H-1-benzopyran-6-carbonitrile
(3β,4α)-3-Hydroxy-2,2-dimethyl-4-(2-oxopyrrolidin-1-yl)chroman-6-carbonitrile
2H-1-Benzopyran-6-carbonitrile, 3,4-dihydro-3-hydroxy-2,2-dimethyl-4-(2-oxo-1-pyrrolidinyl)-, (3S,trans)-
Brn 3622889
LevkroMakaliM
(3S,4R)-3-hydroxy-2,2-dimethyl-4-(2-oxopyrrolidin-1-yl)chroman-6-carbonitrile
2H-1-Benzopyran-6-carbonitrile, 3,4-dihydro-3-hydroxy-2,2-dimethyl-4-(2-oxo-1-pyrrolidinyl)-, (3S,4R)-
Potassium Channel,KcsA,Inhibitor,inhibit,BRL38227,BRL-38227,Levcromakalim
94535-50-9
Ion Channels
Monovalent Ion Channels
Potassium Channel Modulators
Voltage-gated Ion Channels
Cell Signaling and Neuroscience
Cell Biology
BioChemical