(Hexahydro-2,4-methano-4H-furo[3,2-b]pyrrol-3-yl)methylcarbamic acid [6-acetylamino-4-chloro-1-azabicyclo[3.3.0]octan-7-yl] ester

(Hexahydro-2,4-methano-4H-furo[3,2-b]pyrrol-3-yl)methylcarbamic acid [6-acetylamino-4-chloro-1-azabicyclo[3.3.0]octan-7-yl] ester Struktur
60092-32-2
CAS-Nr.
60092-32-2
Englisch Name:
(Hexahydro-2,4-methano-4H-furo[3,2-b]pyrrol-3-yl)methylcarbamic acid [6-acetylamino-4-chloro-1-azabicyclo[3.3.0]octan-7-yl] ester
Synonyma:
Lolidine;(Hexahydro-2,4-methano-4H-furo[3,2-b]pyrrol-3-yl)methylcarbamic acid [6-acetylamino-4-chloro-1-azabicyclo[3.3.0]octan-7-yl] ester;Carbamic acid, (hexahydro-2,4-methano-4H-furo[3,2-b]pyrrol-3-yl)methyl-, 1-(acetylamino)-7-chlorohexahydro-1H-pyrrolizin-2-yl ester (9CI)
CBNumber:
CB52329223
Summenformel:
C18H27ClN4O4
Molgewicht:
398.88
MOL-Datei:
60092-32-2.mol

(Hexahydro-2,4-methano-4H-furo[3,2-b]pyrrol-3-yl)methylcarbamic acid [6-acetylamino-4-chloro-1-azabicyclo[3.3.0]octan-7-yl] ester Eigenschaften

Siedepunkt:
594.3±50.0 °C(Predicted)
Dichte
1.42±0.1 g/cm3(Predicted)
pka
14.37±0.60(Predicted)

Sicherheit

(Hexahydro-2,4-methano-4H-furo[3,2-b]pyrrol-3-yl)methylcarbamic acid [6-acetylamino-4-chloro-1-azabicyclo[3.3.0]octan-7-yl] ester Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Russian workers have recently re-examined the alkaloidal extract of the seeds of Lotium cuneatum and shown that, in addition to a number of simple pyrrolizidine bases, it also contains this novel dimeric alkaloid. Lolidine is one of the few bases found in this plant which contains chlorine in the molecule. The base may be separated from the total alkaloids on a silica gel column from Et20 solution. Treatment with either Ac20 or AcCl fails to give the acetyl derivative confirming that the fourth oxygen atom is present in the form of an ether bridge.

Einzelnachweise

Batirov, Malikov, Yunusov, Khim. Prir. Soedin., 12,63 (1976)

(Hexahydro-2,4-methano-4H-furo[3,2-b]pyrrol-3-yl)methylcarbamic acid [6-acetylamino-4-chloro-1-azabicyclo[3.3.0]octan-7-yl] ester Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


(Hexahydro-2,4-methano-4H-furo[3,2-b]pyrrol-3-yl)methylcarbamic acid [6-acetylamino-4-chloro-1-azabicyclo[3.3.0]octan-7-yl] ester Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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  • (Hexahydro-2,4-methano-4H-furo[3,2-b]pyrrol-3-yl)methylcarbamic acid [6-acetylamino-4-chloro-1-azabicyclo[3.3.0]octan-7-yl] ester
  • Lolidine
  • Carbamic acid, (hexahydro-2,4-methano-4H-furo[3,2-b]pyrrol-3-yl)methyl-, 1-(acetylamino)-7-chlorohexahydro-1H-pyrrolizin-2-yl ester (9CI)
  • 60092-32-2
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