Guanosine 3,5-cyclic Monophosphorothioate, 8-Bromo-, Rp-Isomer, Sodium Salt - Calbiochem Chemische Eigenschaften,Einsatz,Produktion Methoden
Allgemeine Beschreibung
A potent, cell-permeable, and metabolically stable inhibitor of protein kinase G (PKG; K
i = 4 μM). Acts as a cyclic nucleotide-gated channel agonist (EC
50 = 173.5 μM). Significantly more lipophilic and membrane-permeable than cGMP or Rp-cGMPS. Resistant to mammalian cyclic nucleotide-dependent phosphodiesterases. Note: 5 μmol = 2.31 mg.
Biochem/physiol Actions
Cell permeable: yes
Guanosine 3,5-cyclic Monophosphorothioate, 8-Bromo-, Rp-Isomer, Sodium Salt - Calbiochem Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte