Guanosine 3,5-cyclic Monophosphorothioate, 8-Bromo-, Rp-Isomer, Sodium Salt - Calbiochem

Guanosine 3,5-cyclic Monophosphorothioate, 8-Bromo-, Rp-Isomer, Sodium Salt - Calbiochem Struktur
CAS-Nr.
Englisch Name:
Guanosine 3,5-cyclic Monophosphorothioate, 8-Bromo-, Rp-Isomer, Sodium Salt - Calbiochem
Synonyma:
Guanosine 3,5-cyclic Monophosphorothioate, 8-Bromo-, Rp-Isomer, Sodium Salt - Calbiochem
CBNumber:
CB54817241
Summenformel:
Molgewicht:
0
MOL-Datei:
Mol file

Guanosine 3,5-cyclic Monophosphorothioate, 8-Bromo-, Rp-Isomer, Sodium Salt - Calbiochem Eigenschaften

Sicherheit

Guanosine 3,5-cyclic Monophosphorothioate, 8-Bromo-, Rp-Isomer, Sodium Salt - Calbiochem Chemische Eigenschaften,Einsatz,Produktion Methoden

Allgemeine Beschreibung

A potent, cell-permeable, and metabolically stable inhibitor of protein kinase G (PKG; Ki = 4 μM). Acts as a cyclic nucleotide-gated channel agonist (EC50 = 173.5 μM). Significantly more lipophilic and membrane-permeable than cGMP or Rp-cGMPS. Resistant to mammalian cyclic nucleotide-dependent phosphodiesterases. Note: 5 μmol = 2.31 mg.

Biochem/physiol Actions

Cell permeable: yes

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