Albiglutide

Albiglutide Struktur
782500-75-8
CAS-Nr.
782500-75-8
Englisch Name:
Albiglutide
Synonyma:
Albugon;Gsk 716155;albiglutide;Naliglutide;Unii-5E7U48495e;Albiglutide Fragment;Albiglutide(Acetate);Albiglutide USP/EP/BP;Research Grade Albiglutide;7-36-Glucagon-like peptide I (8-glycine) (human), fusion protein with 7-36-glucagon-like peptide I (8-glycine) (human) fusion protein with serum
CBNumber:
CB61518490
Summenformel:
C148H223N39O46
Molgewicht:
3284.58792
MOL-Datei:
782500-75-8.mol

Albiglutide Eigenschaften

storage temp. 
Store at -20°C
Wasserlöslichkeit
Water: 100 mg/mL (30.45 mM);
InChIKey
OGWAVGNOAMXIIM-VTAHJYCESA-N

Sicherheit

Giftige Stoffe Daten 782500-75-8(Hazardous Substances Data)

Albiglutide Chemische Eigenschaften,Einsatz,Produktion Methoden

Allgemeine Beschreibung

Albiglutide (also known as naliglutide, GSK 716155) isa sequential dimer of GLP-1(7–36)(Ala8→Gly) covalentlylinked to modified human serum albumin (i.e., it is a “fusionprotein” with modified HSA). This molecule is currentlywell into phase III clinical trials. Although albiglutide,if marketed (Syncria, GlaxoSmithKline), will—likeexenatide—be administered by injection, the half-life andduration of 6 to 7 days would allow for weekly administration.

Enzyminhibitor

This GLP-1 agonist and anti-diabetic drug (MW = 72.9 kDa; CAS 782500- 75-8), marketed as Eperzan? and Tanzeum?, by GlaxoSmithKline (GSK) is a dipeptidyl peptidase-4-resistant glucagon-like peptide-1 dimer fused to human albumin. Albiglutide has a half-life of 4-7 days, commending it for biweekly or weekly administration in the treatment of Type 2 diabetes. The half-life is considerably longer than exenatide (Byetta?) and liraglutide (Victoza?).

Albiglutide Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Albiglutide Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 73)Lieferanten
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+8618633865755
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782500-75-8()Verwandte Suche:


  • albiglutide
  • Albugon
  • Naliglutide
  • 7-36-Glucagon-like peptide I (8-glycine) (human), fusion protein with 7-36-glucagon-like peptide I (8-glycine) (human) fusion protein with serum
  • Gsk 716155
  • Unii-5E7U48495e
  • 7-36-Glucagon-likepeptide I [8-glycine] (huMan), fusion protein with 7-36-glucagon-like peptide I[8-glycine] (huMan) fusion protein with seruM albuMin (huMan)
  • Albiglutide Fragment
  • Albiglutide USP/EP/BP
  • Albiglutide(Acetate)
  • Research Grade Albiglutide
  • 782500-75-8
  • GLP
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