Dipeptidyl Peptidase-4 Activity Assay Kit Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
DPP4 Activity Assay Kit has been used to determine the activity of dipeptidyl peptidase-4 (DPP4) in homogenates.
Allgemeine Beschreibung
Dipeptidyl peptidase-4 (DPP4), also known as CD26 and adenosine deaminase complexing protein 2, is a serine exopeptidase that cleaves X-Proline and X-Alanine residues from the N-termini of polypeptides. DPP4 is a transmembrane glycoprotein whose activity regulates the bioactivity of multiple peptides such as growth factors, chemokines, and neuropeptides. DPP4 plays a major role in glucose metabolism via the regulation of glucagon-like peptide-1 and inhibitors of DPP4 are commonly used for the treatment of type 2 diabetes. DPP4 also plays an important role in immune regulation and may play a role in tumor suppression. Deletion of the DPP4 gene affects carbohydrate metabolism which in turn leads to mental retardation and hypotonia. Abnormal expression of the protein is observed during liver regeneration, cirrhosis and liver tumorigenesis.
Dipeptidyl Peptidase-4 Activity Assay Kit Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
