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[S-(R*,S*)]-3,4-Dimethoxy-α1-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isochinolin-5-yl)-o-xylol-α,α'-diol

[S-(R*,S*)]-3,4-dimethoxy-alpha1-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)-o-xylene-alpha,alpha'-diol Struktur
23942-99-6
CAS-Nr.
23942-99-6
Bezeichnung:
[S-(R*,S*)]-3,4-Dimethoxy-α1-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isochinolin-5-yl)-o-xylol-α,α'-diol
Englisch Name:
[S-(R*,S*)]-3,4-dimethoxy-alpha1-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)-o-xylene-alpha,alpha'-diol
Synonyma:
alpha-narcotinediol;(-)-α-Narcotinediol;(-)-α-Narcotinediol, CAS 23942-99-6;1,2-Benzenedimethanol, 3,4-dimethoxy-α1-[(5R)-5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-, (α1S)-;[S-(R*,S*)]-3,4-dimethoxy-alpha1-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)-o-xylene-alpha,alpha'-diol
CBNumber:
CB6911876
Summenformel:
C22H27NO7
Molgewicht:
417.45
MOL-Datei:
23942-99-6.mol
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[S-(R*,S*)]-3,4-Dimethoxy-α1-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isochinolin-5-yl)-o-xylol-α,α'-diol Eigenschaften

Schmelzpunkt:
130-132 °C(Solv: ethyl acetate (141-78-6); ethyl ether (60-29-7))
Siedepunkt:
570.3±50.0 °C(Predicted)
Dichte
1.300±0.06 g/cm3(Predicted)
Löslichkeit
soluble in Chloroform, Dichloromethane, Ethyl Acetate, Methanol
Aggregatzustand
Solid
pka
13.25±0.20(Predicted)
Farbe
White

Sicherheit

[S-(R*,S*)]-3,4-Dimethoxy-α1-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isochinolin-5-yl)-o-xylol-α,α'-diol Chemische Eigenschaften,Einsatz,Produktion Methoden

Chemische Eigenschaften

White Solid

Verwenden

(-)-α-Narcotinediol is a Narcotine derivative, a noscapinoid class of microtubule binding compounds that alter microtubule dynamics without affecting tubulin polymer mass. Noscapinoids show great promise as chemotherapeutic agents for the treatment of human cancers. Unlike Narcotine, (-)-α-Narcotinediol deos not inhibit small-intestinal transport in rats.

[S-(R*,S*)]-3,4-Dimethoxy-α1-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isochinolin-5-yl)-o-xylol-α,α'-diol Upstream-Materialien And Downstream Produkte

Upstream-Materialien

(+)-Papaveroxinoline Noscapin

Downstream Produkte

[S-(R*,S*)]-3,4-Dimethoxy-α1-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isochinolin-5-yl)-o-xylol-α,α'-diol Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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  • [S-(R*,S*)]-3,4-dimethoxy-alpha1-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)-o-xylene-alpha,alpha'-diol
  • alpha-narcotinediol
  • 1,2-Benzenedimethanol, 3,4-dimethoxy-α1-[(5R)-5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-, (α1S)-
  • (-)-α-Narcotinediol
  • (-)-α-Narcotinediol, CAS 23942-99-6
  • 23942-99-6
  • Pharmaceuticals, Intermediates & Fine Chemicals
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