Furin Inhibitor II - Calbiochem Chemische Eigenschaften,Einsatz,Produktion Methoden
Allgemeine Beschreibung
A polyarginine compound that acts as a potent, specific, and competitive inhibitor of furin (K
i = 106 nM). Inhibits Subtilisin-like proprotein convertase 4 (PACE4) and prohormone convertase 1 (PC1) at much higher concentration (K
i = 580 nM and 13 μM, respectively). Has a stimulatory effect on the activity of prohormone convertase 2 (PC2). The D-peptides are suggested to be more resistant to
in vivo hydrolysis than L-peptides.
Biochem/physiol Actions
Primary Targetfurin
Furin Inhibitor II - Calbiochem Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
