Natrium-4-hydroxybutyrat
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- CAS-Nr.
- 502-85-2
- Bezeichnung:
- Natrium-4-hydroxybutyrat
- Englisch Name:
- SODIUM 4-HYDROXYBUTYRATE
- Synonyma:
- GHB;SODIUM OXYBATE;SODIUM 4-HYDROXYBUTANOATE;gammaoh;wy-3478;somsanit;NSC-84223;GHB SODIUM SALT;Oxybate (sodium);Levetiracetam-15
- CBNumber:
- CB7491645
- Summenformel:
- C4H9NaO3
- Molgewicht:
- 128.1
- MOL-Datei:
- 502-85-2.mol
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Natrium-4-hydroxybutyrat Eigenschaften
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| Kennzeichnung gefährlicher |
F,T |
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| R-Sätze: |
11-23/24/25-39/23/24/25 |
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| S-Sätze: |
22-24/25-45-36/37-16-7 |
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| RIDADR |
UN1230 - class 3 - PG 2 - Methanol, solution |
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| WGK Germany |
2 |
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| RTECS-Nr. |
ET4750000 |
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| F |
3 |
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| HazardClass |
IRRITANT |
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| Toxizität |
Highly sol in aq solns. LD50 in male, female rats (mg/kg): 2,000, 1,650 i.p. (Bruguerolle) |
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| Bildanzeige (GHS) |
  
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| Alarmwort |
Achtung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H225 |
Flüssigkeit und Dampf leicht entzündbar. |
Entzündbare Flüssigkeiten |
Kategorie 2 |
Achtung |
![GHS hazard pictograms]() src="/GHS02.jpg" width="20" height="20" /> |
P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501 |
| H370 |
Schädigt die Organe. |
Spezifische Zielorgan-Toxizität (einmalige Exposition) |
Kategorie 1 |
Achtung |
![GHS hazard pictograms]() src="/GHS08.jpg" width="20" height="20" /> |
P260, P264, P270, P307+P311, P321,P405, P501 |
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| Sicherheit |
| P210 |
Von Hitze, heißen Oberflächen, Funken, offenen Flammen und anderen Zündquellenarten fernhalten. Nicht rauchen. |
| P260 |
Dampf/Aerosol/Nebel nicht einatmen. |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P301+P310 |
BEI VERSCHLUCKEN: Sofort GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen. |
| P311 |
GIFTINFORMATIONSZENTRUM/Arzt anrufen. |
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Natrium-4-hydroxybutyrat Chemische Eigenschaften,Einsatz,Produktion Methoden
S-Sätze Betriebsanweisung:
S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
Beschreibung
Xyrem is distributed by Jazz Pharmaceuticals, Inc. (Palo Alto,
CA). It is an oral solution of sodium oxybate prescribed for
narcoleptic patients to treat extreme daytime sleepiness and
cataplexy. Xyrem is also known as sodium oxybate which is the
same as gamma hydroxybutyric acid (GHB), a drug of abuse.
GHB is endogenously produced and present in the central
nervous system (CNS) in small concentrations. Accidental
overdosing has led to many hospitalizations and deaths.
Because of the tendency to abuse GHB, it was classified as
a schedule I controlled substance. This meant that GHB had
a high potential for abuse and no medical purpose. However,
in 2002, because of a series of clinical trials that demonstrated
that the compound reduces cataplexy attacks, it was approved
for use under the trademark Xyrem. Since GHB had previously
been used as a ‘date-rape’ drug, Xyrem is considered a schedule
III controlled substance and is distributed in accordance with
strict FDA regulations. Xyrem may only be ordered through the
‘Xyrem Success Program.’ Illegal use is punishable under
federal and state laws.
Chemische Eigenschaften
white crystalline powder
Verwenden
4-Hydroxybutyric acid sodium salt is an agonist to both GHB and GABAB neural receptors, exhibiting neurotransmitter-like effects. It has been used as a general anesthetic in treatment for sleep disorders and clinical depression, but also has been identified as a “date rape drug”.
Environmental Fate
Xyrem is a water-soluble white to off-white powder, which can
be disposed by dumping the oral solution down the sanitary
sewer system. This is the preferred method of disposal for drugs
which have a high potential for abuse and/or accidental
overdose.
Natrium-4-hydroxybutyrat Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Natrium-4-hydroxybutyrat Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 95)Lieferanten
502-85-2(Natrium-4-hydroxybutyrat)Verwandte Suche:
- 4-hydroxy-butanoicacimonosodiumsalt
- 4-hydroxy-butyricacisodiumsalt
- γ-Hydroxybutyric acid sodium salt
- GAMMA-HYDROXYBUTYRIC ACID SODIUM
- Sodium4-hydroxybutyrate,98%
- Butanoic acid, 4-hydroxy-, monosodium salt
- GHB,1.0MG/MLINMETHANOL
- Sodium oxybutryrate (gamma)
- γ-Hydroxybutyric acid sodium salt, 4-Hydroxybutyric acid sodium salt, GHB, Sodium 4-hydroxybutyrate
- 4-Hydroxybutanoic acid sodium
- NSC-84223
- 4-Hydroxybutyric acid, sodium salt,99%
- Methanol (test GHB Sodium Salt, 1.0 mg/mL)
- Sodium g-hydroxybutyrate (GHB)
- 4-Hydroxybutyrate sodium
- 4-Hydroxybutyric acid monosodium salt
- Butanoic acid,4-hydroxy-, sodiuM salt (1:1)
- GHB SODIUM SALT
- GAMMA-HYDROXYBUTYRIC ACID SODIUM SALT
- 4-Hydroxybutyric acid sodium salt solution
- GHB sodium salt solution
- Oxybate (sodium)
- gamma-hydroxybutyratesodiumsalt
- gammaoh
- sodiumgamma-hydroxybutyrate
- somsanit
- wy-3478
- 4-HYDROXYBUTANOIC ACID SODIUM SALT
- 4-HYDROXYBUTYRIC ACID SODIUM SALT
- SODIUM 4-HYDROXYBUTYRATE
- SODIUM OXYBATE SODIUM SALT
- SODIUM GAMMA-HYDROXY-N-BUTYRATE
- Levetiracetam-15
- γ-Hydroxybutyric acid monosodium salt
- Levetiracetam Impurity O
- Levetiracetam Impurity P
- (S)-isopropyl 2-(2-oxopyrrolidin-1-yl)butanoate
- 4-Hydroxybutanoic acid sodium salt Solution, 1000ppm
- GHB (sodium salt) (exempt preparation)
- Levetiracetam Impurity 22/4-Hydroxybutyrate sodium
- SODIUM 4-HYDROXYBUTYRATE USP/EP/BP
- Levetiracetam impurities509
- GHB
- SODIUM 4-HYDROXYBUTANOATE
- SODIUM OXYBATE
- GHB Sodium Salt (Sodium Gammahydroxybutyrate)
- *Levetiracetam Impurity 19 (Gamma-hydroxybutyrate Sodium Salt)
- γ-Hydroxybutyric Acid Sodium Salt
- 502-85-2
- HOCH23COONa
- C4H7O3種a
- GABA and Glycine Receptor Modulators
- Cell Signaling and Neuroscience
- Cell Biology
- BioChemical
- Ion Channels
- Ligand-Gated Ion Channels
- Aliphatics
