ANTI-ANG-1

ANTI-ANG-1 Struktur
CAS-Nr.
Englisch Name:
ANTI-ANG-1
Synonyma:
ANTI-ANG-1;Anti-NET47;Anti-DHCR14A;Anti-EIF3EIPP2;Anti-EIF3S6IPP2;ANTI-ANGIOPOIETIN-1;MONOCLONAL ANTI-ANGIOPOIETIN-1;Anti-TM7SF2 antibody produced in rabbit;Anti-ANGPT1 antibody produced in rabbit;Anti-transmembrane 7 superfamily member 2
CBNumber:
CB7783704
Summenformel:
Molgewicht:
0
MOL-Datei:
Mol file

ANTI-ANG-1 Eigenschaften

storage temp. 
-20°C
Aggregatzustand
lyophilized powder

Sicherheit

WGK Germany  3

ANTI-ANG-1 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunohistochemistry (1 paper)

Allgemeine Beschreibung

Anti-Angiopoietin-1 detects recombinant human angiopoietin-1. The antibody shows no cross-reactivity with recombinant human angiopoietin-2, recombinant human angiopoietin-4, recombinant mouse angiopoietin-like 3, and recombinant human cornea-derived transcript 6 (CDT-6).The ANG-1 gene is mapped to human chromosome 8q23.1.

Biochem/physiol Actions

Angiopoietin 1 is an endothelial cell-specific protein that is a ligand for the TIE2 tyrosine receptor. It is required for mature blood vessel formation .Angiopoietins are growth factors vital for vascular differentiation during normal development. There are four angiopoietins discovered that bind to receptor tyrosine kinases Tie2. Angiopoietin-1 (ANG-1) is a potent pro-angiogenic factor that works by recruits mural cells for endothelial tubule formation and vessel maturation. ANG-1 acts along with VEGF in enhance angiogenesis and increase vascular branching. ANG-1 also affects the inflammatory process and inhibits the capillary transmigration of leukocytes on TNF-α stimulation. Sonic hedgehog, a secreted growth factor, reportedly upregulates the expression of ANG-1. Overexpression of angiopoietins has been observed in a variety of malignancies including neuroblastoma, glioblastoma and lung cancers. While ANG-2 increases the metastasis and angiogenesis of the tumors, ANG-1 inhibits tumor angiogenesis

ANTI-ANG-1 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


ANTI-ANG-1 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 3)Lieferanten
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  • ANTI-ANGIOPOIETIN-1
  • ANTI-ANG-1
  • MONOCLONAL ANTI-ANGIOPOIETIN-1
  • Anti-Angiopoietin-1 antibody produced in goat
  • Monoclonal Anti-Angiopoietin-1 antibody produced in mouse
  • Anti-DHCR14A
  • Anti-EIF3EIPP2
  • Anti-EIF3S6IPP2
  • Anti-NET47
  • Anti-TM7SF2 antibody produced in rabbit
  • Anti-transmembrane 7 superfamily member 2
  • Anti-TM7SF2, (N-terminal) antibody produced in rabbit
  • Anti-ANGPT1 antibody produced in rabbit
  • Tie
  • Receptor Tyrosine Kinase Antibodies
  • Primary Antibodies
  • BioChemical
  • Cell Biology
  • Antibodies
  • Antibodies for Kinase/Phosphatase Biology
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