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2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]aniline

2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]aniline Struktur
761440-75-9
CAS-Nr.
761440-75-9
Englisch Name:
2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]aniline
Synonyma:
2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]aniline;WDQZQPCYVLHWRA;Brigatinib Impurity 3;2-Methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidyl]aniline;2-Methoxy-4-[4-(-methylpiperazine-1-yl)piperidin-1-yl]amine;2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)anilin;2-Methoxy-4-(4-(4-Methylpiperazin-1-yl)piperidin-1-yl)benzenaMine;2-Methoxy-4-[4-(4-Methyl-1-piperazinyl)-1-piperidinyl]-BenzenaMine;[2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]amine;Benzenamine, 2-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]-
CBNumber:
CB82473938
Summenformel:
C17H28N4O
Molgewicht:
304.43
MOL-Datei:
761440-75-9.mol
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2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]aniline Eigenschaften

Siedepunkt:
479.3±45.0 °C(Predicted)
Dichte
1.126±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
pka
8.14±0.42(Predicted)
InChI
InChI=1S/C17H28N4O/c1-19-9-11-21(12-10-19)14-5-7-20(8-6-14)15-3-4-16(18)17(13-15)22-2/h3-4,13-14H,5-12,18H2,1-2H3
InChIKey
WDQZQPCYVLHWRA-UHFFFAOYSA-N
SMILES
C1(N)=CC=C(N2CCC(N3CCN(C)CC3)CC2)C=C1OC
Sicherheit
  • Risiko- und Sicherheitserklärung
  • Gefahreninformationscode (GHS)
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizität (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" />
Sicherheit
P261 Einatmen von Staub vermeiden.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen.

2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]aniline Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]aniline is a cycloalkylamine analogue that can be used as a component of organic synthesis intermediates for the synthesis of the active compound ASP3026. ASP3026 is an orally available receptor tyrosine kinase anaplastic lymphoma kinase (ALK) small molecule inhibitor with promising anti-tumour and apoptosis-inducing effects, which has been used in the study of solid tumours, B-cell lymphomas, advanced malignant tumours, interstitial lymphoma kinase-positive and proto-oncogene tyrosine protein kinase ROS-positive therapy.

Verwenden

[2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]amine is an intermediate of Brigatinib which is a medicine used to treat cancer that suppresses epidermal growth factor receptor (EGFR) and anaplastic lymphoma kinase (ALK).

2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]aniline Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

N2-[2-Methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-1,3,5-triazine-2,4-diamine

2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]aniline Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 184)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Enki Biopharmaceuticals (Shanghai) Limited
+86-0086-2157680326 +8613916707528
 yusu@enkibiopharma.com China 46 58
Henan Fengda Chemical Co., Ltd 		+86-371-86557731 +86-13613820652
 info@fdachem.com China 20293 58
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512
 info@tianfuchem.com China 21667 55
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795
ivan@atkchemical.com China 32836 60
Anqing Chico Pharmaceutical Co., Ltd. 		15380796838
chloewu@chicopharm.cn CHINA 341 58
career henan chemical co 		+86-0371-86658258 +8613203830695
 sales@coreychem.com China 29888 58
TianYuan Pharmaceutical CO.,LTD 		+86-755-23284190 13684996853
sales@tianpharm.com CHINA 304 58
Shandong chuangyingchemical Co., Ltd. 		18853181302
sale@chuangyingchem.com CHINA 5909 58
Chongqing Chemdad Co., Ltd 		+86-023-6139-8061 +86-86-13650506873
 sales@chemdad.com China 39916 58
Alchem Pharmtech,Inc. 		8485655694
sales@alchempharmtech.com United States 63711 58

761440-75-9()Verwandte Suche:

1-[4-(Trifluormethyl)phenyl]piperazin 2-Methylpiperazin 1-Methylpiperazin
  • [2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]amine
  • 2-Methoxy-4-(4-(4-Methylpiperazin-1-yl)piperidin-1-yl)benzenaMine
  • 2-Methoxy-4-[4-(4-Methyl-1-piperazinyl)-1-piperidinyl]-BenzenaMine
  • 2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)anilin
  • [2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]amine,761440-75-9
  • [2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]amine ISO 9001：2015 REACH
  • Benzenamine, 2-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]-
  • WDQZQPCYVLHWRA
  • 2-Methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidyl]aniline
  • 2-methoxy-4- [4- (4-methyl-1-piperazinyl) -1-piperazinyl] - aniline hydrochloride
  • 2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]aniline
  • 2-methoxy-4-[4-(4-methy l-1-piperazinyl)-1-pipe razinyl]-aniline hydrochlorid
  • Aniline 2-methoxy-4 - [4 - (4-methyl-1-piperazinyl) - 1-piperazinyl] - hydrochloride
  • 2- methoxy -4-[4-(4- methylpiperazine -1- yl) piperidin -1- yl] aniline *
  • Brigatinib Impurity 3
  • 2-Methoxy-4-[4-(-methylpiperazine-1-yl)piperidin-1-yl]amine
  • 761440-75-9
  • C17H28N4O
  • 761440-75-9
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