Anti-Gonadotropin-Releasing Hormone Antibody, NT, clone HU11B (Ascites Free)

Anti-Gonadotropin-Releasing Hormone Antibody, NT, clone HU11B (Ascites Free) Struktur
CAS-Nr.
Englisch Name:
Anti-Gonadotropin-Releasing Hormone Antibody, NT, clone HU11B (Ascites Free)
Synonyma:
Anti-Gonadotropin-Releasing Hormone Antibody, NT, clone HU11B (Ascites Free)
CBNumber:
CB84816144
Summenformel:
Molgewicht:
0
MOL-Datei:
Mol file

Anti-Gonadotropin-Releasing Hormone Antibody, NT, clone HU11B (Ascites Free) Eigenschaften

Sicherheit

Anti-Gonadotropin-Releasing Hormone Antibody, NT, clone HU11B (Ascites Free) Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Research Category
Neuroscience

Allgemeine Beschreibung

Gonadotropin-releasing hormone I (also known as GnRH, GnRH-I, Gonadoliberin-1, Gonadoliberin I, LHRH, LH-RH I, Luteinizing hormone-releasing hormone I) is encoded by the Gnrh1 (also known as Gnrh, Lhrh1, Lnrh) gene (Gene ID 14714) in murine species. GnRH/LHRH is initially produced as a 90-amino acid progonadoliberin-1 precursor protein (UniProt P13562), removal of the signal peptide (a.a. 1-21) yields progonadoliberin-1 (a.a. 22-90), which is further processed by a proteolytic cleavage to release the GnRH/LHRH decapeptide (a.a. 22-31) and the 56-a.a. prolactin release-inhibiting factor 1 (a.a. 35-90). The LHRH decapeptide functions as the primary endocrine link between the brain and the reproductive system. It plays a primary neuroendocrine role in orchestrating the developmental processes associated with sexual development in immature mammals and also in maintaining normal reproductive function in adults. LHRH-producing neurons are located mainly in the lateral anterior hypothalamus, septum, and medial preoptic area, from where they extend axons towards the median eminence and relese the hormone into the hypothalamo-hypophyseal portal blood vessels in an episodic or pulsatile manner.

Anti-Gonadotropin-Releasing Hormone Antibody, NT, clone HU11B (Ascites Free) Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


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