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BMS-986020

BMS-986020 Struktur
1257213-50-5
CAS-Nr.
1257213-50-5
Englisch Name:
BMS-986020
Synonyma:
AM152;CS-2492;BMS-986020;AP-3152 free acid;BMS-986020;BMS 986020;BMS986020;1-{4'-[3-methyl-4-((R)-1-phenyl-ethoxycarbonylamino)-isoxazol-5-yl]-biphenyl-4-yl}-cyclopropanecarboxylic acid;(R)-1-(4'-(3-Methyl-4-(((1-phenylethoxy)carbonyl)amino)isoxazol-5-yl)-[1,1'-biphenyl]-4-yl)cyclopropane-1-carboxylic acid;Cyclopropanecarboxylic acid, 1-[4'-[3-methyl-4-[[[(1R)-1-phenylethoxy]carbonyl]amino]-5-isoxazolyl][1,1'-biphenyl]-4-yl]-;(R)-1-(4'-(3-methyl-4-(((1-phenylethoxy)carbonyl)amino)isoxazol-5-yl)-[1,1'-biphenyl]-4-yl)cyclopropane-1-carboxylic acid;inhibit,idiopathic,AM-152,LPL Receptor,Lysophospholipid Receptor,AM 152,IPF,BMS-986020,fibrosis,pulmonary,BMS 986020,autoradiography,Inhibitor,ARG
CBNumber:
CB93070650
Summenformel:
C29H26N2O5
Molgewicht:
482.53
MOL-Datei:
1257213-50-5.mol
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BMS-986020 Eigenschaften

Schmelzpunkt:
174-180°C
Siedepunkt:
664.8±55.0 °C(Predicted)
Dichte
1.309±0.06 g/cm3(Predicted)
storage temp. 
-20°C Freezer
Löslichkeit
DMSO (Slightly), Methanol (Slightly, Sonicated)
Aggregatzustand
Solid
pka
4.19±0.20(Predicted)
Farbe
White to Off-White

Sicherheit

BMS-986020 Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

BMS 986020 is a potent G protein-coupled lysophosphatidic acid receptor 1 (LPA1) antagonist with an IC50 value less than 300 nM for human LPA1 expressing CHO cells. Formulations containing BMS 986020 are being investigated in clinical trials for efficacy in idiopathic pulmonary fibrosis.

BMS-986020 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

BMS-986020 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 66)Lieferanten
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  • BMS-986020
  • CS-2492
  • (R)-1-(4'-(3-methyl-4-(((1-phenylethoxy)carbonyl)amino)isoxazol-5-yl)-[1,1'-biphenyl]-4-yl)cyclopropane-1-carboxylic acid
  • BMS-986020;BMS 986020;BMS986020
  • 1-{4'-[3-methyl-4-((R)-1-phenyl-ethoxycarbonylamino)-isoxazol-5-yl]-biphenyl-4-yl}-cyclopropanecarboxylic acid
  • AM152
  • Cyclopropanecarboxylic acid, 1-[4'-[3-methyl-4-[[[(1R)-1-phenylethoxy]carbonyl]amino]-5-isoxazolyl][1,1'-biphenyl]-4-yl]-
  • inhibit,idiopathic,AM-152,LPL Receptor,Lysophospholipid Receptor,AM 152,IPF,BMS-986020,fibrosis,pulmonary,BMS 986020,autoradiography,Inhibitor,ARG
  • AP-3152 free acid
  • (R)-1-(4'-(3-Methyl-4-(((1-phenylethoxy)carbonyl)amino)isoxazol-5-yl)-[1,1'-biphenyl]-4-yl)cyclopropane-1-carboxylic acid
  • 1257213-50-5
  • 257213-50-5
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