Autocamtide-2 Related Inhibitory Peptide II - Calbiochem

Autocamtide-2 Related Inhibitory Peptide II - Calbiochem Chemische Eigenschaften,Einsatz,Produktion Methoden

Allgemeine Beschreibung

An autocamtide-2 related inhibitory peptide (AIP) analog in which Ala³ and Val¹⁰ have been replaced with Lys and Phe, respectively. Acts as a highly specific, potent inhibitor of calmodulin-dependent protein kinase II (CaMKII) (IC₅₀ = 4.1 nM). Displays ~10-fold greater potency than AIP (Cat. No. 189480). Inhibits PKC at higher concentrations (IC₅₀ = 1 μM), but does not affect the activities of CaMKIV or PKA (IC₅₀ >100 μM).

Biochem/physiol Actions

Primary TargetCAM Kinase-2

Autocamtide-2 Related Inhibitory Peptide II - Calbiochem Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Autocamtide-2 Related Inhibitory Peptide II - Calbiochem Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51471	80

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• Autocamtide-2 Related Inhibitory Peptide II - Calbiochem