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ChemicalBook >> CAS DataBase List >>2-Tetradecanol, 1,1′-[[2-[2-[4-[2-[[2-[2-[bis(2-hydroxytetradecyl)amino]ethoxy]ethyl](2-hydroxytetradecyl)amino]ethyl]-1-piperazinyl]ethoxy]ethyl]imino]bis-

2-Tetradecanol, 1,1′-[[2-[2-[4-[2-[[2-[2-[bis(2-hydroxytetradecyl)amino]ethoxy]ethyl](2-hydroxytetradecyl)amino]ethyl]-1-piperazinyl]ethoxy]ethyl]imino]bis-

2-Tetradecanol, 1,1′-[[2-[2-[4-[2-[[2-[2-[bis(2-hydroxytetradecyl)amino]ethoxy]ethyl](2-hydroxytetradecyl)amino]ethyl]-1-piperazinyl]ethoxy]ethyl]imino]bis- Structure
2-Tetradecanol, 1,1′-[[2-[2-[4-[2-[[2-[2-[bis(2-hydroxytetradecyl)amino]ethoxy]ethyl](2-hydroxytetradecyl)amino]ethyl]-1-piperazinyl]ethoxy]ethyl]imino]bis- structure
CAS No.
2639634-80-1
Chemical Name:
2-Tetradecanol, 1,1′-[[2-[2-[4-[2-[[2-[2-[bis(2-hydroxytetradecyl)amino]ethoxy]ethyl](2-hydroxytetradecyl)amino]ethyl]-1-piperazinyl]ethoxy]ethyl]imino]bis-
Synonyms
C14-4;C14-494;Lipid B4;Lipid B4(P05);C14-4 (C14-494,Lipid B-4);C14-4 (C14-494,Lipid B-4,Lipid B4);1-[(2-{2-[bis(2-hydroxytetradecyl)amino]ethoxy}ethyl)({2-[4-(2-{2-[bis(2-hydroxytetradecyl)amino]ethoxy}ethyl)piperazin-1-yl]ethyl})amino]tetradecan-2-ol;2-Tetradecanol, 1,1′-[[2-[2-[4-[2-[[2-[2-[bis(2-hydroxytetradecyl)amino]ethoxy]ethyl](2-hydroxytetradecyl)amino]ethyl]-1-piperazinyl]ethoxy]ethyl]imino]bis-;1,1'-((2-(2-(4-(2-((2-(2-(Bis(2-hydroxytetradecyl)amino)ethoxy)ethyl)(2-hydroxytetradecyl)amino)ethyl)piperazin-1-yl)ethoxy)ethyl)azanediyl)bis(tetradecan-2-ol)
CBNumber:
CB010532463
Molecular Formula:
C84H173N5O7
Molecular Weight:
1365.3
MDL Number:
MOL File:
2639634-80-1.mol
Last updated:2025-12-10 09:00:29
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2-Tetradecanol, 1,1′-[[2-[2-[4-[2-[[2-[2-[bis(2-hydroxytetradecyl)amino]ethoxy]ethyl](2-hydroxytetradecyl)amino]ethyl]-1-piperazinyl]ethoxy]ethyl]imino]bis- Properties

Boiling point 1123.5±65.0 °C(Predicted)
Density 0.946±0.06 g/cm3(Predicted)
solubility Ethanol: 10 mg/ml
pka 14.41±0.20(Predicted)
form Liquid
color Colorless to light yellow

2-Tetradecanol, 1,1′-[[2-[2-[4-[2-[[2-[2-[bis(2-hydroxytetradecyl)amino]ethoxy]ethyl](2-hydroxytetradecyl)amino]ethyl]-1-piperazinyl]ethoxy]ethyl]imino]bis- Chemical Properties,Uses,Production

Uses

C14-4 is an ionizable lipid utilized for the synthesis of lipid nanoparticles (LNPs). C14-4 enhances mRNA delivery, enabling the effective transport of mRNA to primary human T cells, which in turn induces functional protein expression. C14-4 demonstrates high transfection efficiency while maintaining low cytotoxicity[1].

References

[1] Billingsley MM, et al. Ionizable Lipid Nanoparticle-Mediated mRNA Delivery for Human CAR T Cell Engineering. Nano Lett. 2020 Mar 11;20(3):1578-1589. DOI:10.1021/acs.nanolett.9b04246
[2] MARGARET M. BILLINGSLEY. Orthogonal Design of Experiments for Optimization of Lipid Nanoparticles for mRNA Engineering of CAR T Cells[J]. Nano Letters, 2021, 22 1: 533-542. DOI: 10.1021/acs.nanolett.1c02503
[3] SAVAN K PATEL. Bile acid-containing lipid nanoparticles enhance extrahepatic mRNA delivery.[J]. Theranostics, 2024, 14 1: 1-16. DOI: 10.7150/thno.89913

2-Tetradecanol, 1,1′-[[2-[2-[4-[2-[[2-[2-[bis(2-hydroxytetradecyl)amino]ethoxy]ethyl](2-hydroxytetradecyl)amino]ethyl]-1-piperazinyl]ethoxy]ethyl]imino]bis- Preparation Products And Raw materials

Raw materials

Preparation Products

2-Tetradecanol, 1,1′-[[2-[2-[4-[2-[[2-[2-[bis(2-hydroxytetradecyl)amino]ethoxy]ethyl](2-hydroxytetradecyl)amino]ethyl]-1-piperazinyl]ethoxy]ethyl]imino]bis- Suppliers

Global( 23)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354; support@targetmol.com United States 39035 58
Hubei Chuchang Biotech Co., Ltd. 		+undefined15623860702 info@chuchangbiotech.com China 202 58
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696，15000506266 15000506266 China 4768 55
Shanghai JingRon Chemical Technology Co., Ltd. 021-60546673 13701861782 kuanga111@sina.com China 932 58
Shanghai Jingjinchem Co., Ltd. 021-13817626287 13817626287 1094777898@qq.com China 110 55
Shanghai Chaolan Chemical Technology Center 021-QQ：65489617 15618227136 Sales@ATKchemical.com China 9125 58
Shanghai Changyu Medical Technology Co. Ltd. +86-13301875428 sales@changyuhe.com China 311 58
Shochem(Shanghai)Co.,Ltd +86-021-51783479 +86-13816874662 info@shochem.com China 307 58
DC Chemicals 021-58447131 13564518121 doncunbiosci@gmail.com China 544 58
Wuxi Donghe Pharmaceutical Technology Co., Ltd. 63313187 15358055255 63313187@qq.com China 1984 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
Hubei Chuchang Biotech Co., Ltd. 		58
Shanghai Lollane Biological Technology Co.,Ltd. 55
Shanghai JingRon Chemical Technology Co., Ltd. 58
Shanghai Jingjinchem Co., Ltd. 55
Shanghai Chaolan Chemical Technology Center 58
Shanghai Changyu Medical Technology Co. Ltd. 58
Shochem(Shanghai)Co.,Ltd 58
DC Chemicals 58
Wuxi Donghe Pharmaceutical Technology Co., Ltd. 58

View Lastest Price from 2-Tetradecanol, 1,1′-[[2-[2-[4-[2-[[2-[2-[bis(2-hydroxytetradecyl)amino]ethoxy]ethyl](2-hydroxytetradecyl)amino]ethyl]-1-piperazinyl]ethoxy]ethyl]imino]bis- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
C14-4 pictures 2025-12-09 C14-4
2639634-80-1
 US $322.00-198.00 / mg 99.59% 10g TargetMol Chemicals Inc.
  • C14-4 pictures
  • C14-4
    2639634-80-1
  • US $322.00-198.00 / mg
  • 99.59%
  • TargetMol Chemicals Inc.
C14-4 (C14-494,Lipid B-4) C14-4 C14-4 (C14-494,Lipid B-4,Lipid B4) 1-[(2-{2-[bis(2-hydroxytetradecyl)amino]ethoxy}ethyl)({2-[4-(2-{2-[bis(2-hydroxytetradecyl)amino]ethoxy}ethyl)piperazin-1-yl]ethyl})amino]tetradecan-2-ol 2-Tetradecanol, 1,1′-[[2-[2-[4-[2-[[2-[2-[bis(2-hydroxytetradecyl)amino]ethoxy]ethyl](2-hydroxytetradecyl)amino]ethyl]-1-piperazinyl]ethoxy]ethyl]imino]bis- 1,1'-((2-(2-(4-(2-((2-(2-(Bis(2-hydroxytetradecyl)amino)ethoxy)ethyl)(2-hydroxytetradecyl)amino)ethyl)piperazin-1-yl)ethoxy)ethyl)azanediyl)bis(tetradecan-2-ol) C14-494 Lipid B4 Lipid B4(P05) 2639634-80-1 C84H173N5O7