CIS-(+/-)-1-(AMINOMETHYL)-3,4-DIHYDRO-3-PHENYL-1H-2-BENZOPYRAN-5,6-DIOL HYDROCHLORIDE
- CAS No.
- 130465-39-3
- Chemical Name:
- CIS-(+/-)-1-(AMINOMETHYL)-3,4-DIHYDRO-3-PHENYL-1H-2-BENZOPYRAN-5,6-DIOL HYDROCHLORIDE
- Synonyms
- A 68930;A68930HCl;A 68930 hydrochlorid;A 68930 HYDROCHLORIDE;A-68930 hydrochloride (A68930);cis-1-(AMinoMethyl)-3-phenylisochroMan-5,6-diol hydrochloride;(1R,3S)-1-(AMinoMethyl)-3-phenylisochroMan-5,6-diol hydrochloride;(1R,3S)-1-(aminomethyl)-3,4-dihydro-5,6-dihydroxy-3-phenyl-1H-2-benzopyran;1-(aminomethyl)-3,4-dihydro-3-phenyl-1H-2-Benzopyran-5,6-diol hydrochloride;cis-(±)-1-Aminoethyl-3,4-dihydro-3-phenyl-1H-2-benzopyran-5,6-diol hydrochloride
- CBNumber:
- CB0174886
- Molecular Formula:
- C16H18ClNO3
- Molecular Weight:
- 307.77
- MDL Number:
- MFCD05863727
- MOL File:
- 130465-39-3.mol
| storage temp. | −20°C |
|---|---|
| solubility | H2O: ~9 mg/mL, soluble |
| form | solid |
| color | off-white |
| Water Solubility | Soluble to 50 mM in water |
| FDA UNII | B4NI77O5D4 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| Safety Statements | 22-24/25 |
| WGK Germany | 3 |
CIS-(+/-)-1-(AMINOMETHYL)-3,4-DIHYDRO-3-PHENYL-1H-2-BENZOPYRAN-5,6-DIOL HYDROCHLORIDE price More Price(8)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Tocris | 1534 | A-68930 hydrochloride ≥98%(HPLC) | 130465-39-3 | 50 | $682 | 2021-12-16 | Buy |
| Tocris | 1534 | A-68930 hydrochloride ≥98%(HPLC) | 130465-39-3 | 10 | $162 | 2021-12-16 | Buy |
| Usbiological | 254474 | A 68930 hydrochloride | 130465-39-3 | 10mg | $446 | 2021-12-16 | Buy |
| TRC | A965318 | A-68930 hydrochloride | 130465-39-3 | 1mg | $105 | 2021-12-16 | Buy |
| ApexBio Technology | B6779 | A-68930 hydrochloride | 130465-39-3 | 50mg | $990 | 2021-12-16 | Buy |
CIS-(+/-)-1-(AMINOMETHYL)-3,4-DIHYDRO-3-PHENYL-1H-2-BENZOPYRAN-5,6-DIOL HYDROCHLORIDE Chemical Properties,Uses,Production
Uses
A 68930 Hydrochloride is a potent and selective agonist at the D1-like dopamine receptor. It demontrated neuroprotective and anti-stress effects in rat model (1,2).
Biological Activity
Potent and selective D 1 -like dopamine receptor agonist (EC 50 values are 2.1 and 3910 nM for D 1 -like and D 2 -like receptors respectively). Centrally active following systemic administration in vivo .
storage
Desiccate at +4°C
References
[1]. kebabian jw, briggs c, britton dr, et al. a68930: a potent and specific agonist for the d-1 dopamine receptor. am j hypertens, 1990, 3(6 pt 2): 40s-42s.
[2]. salmi p. independent roles of dopamine d1 and d2/3 receptors in rat thermoregulation. brain res, 1998, 781(1-2): 188-193.
[3]. deveney am, waddington jl. psychopharmacological distinction between novel full-efficacy "d1-like" dopamine receptor agonists. pharmacol biochem behav, 1997, 58(2): 551-558.
[4]. rasheed n, ahmad a, al-sheeha m, et al. neuroprotective and anti-stress effect of a68930 in acute and chronic unpredictable stress model in rats. neurosci lett, 2011, 504(2): 151-155.
CIS-(+/-)-1-(AMINOMETHYL)-3,4-DIHYDRO-3-PHENYL-1H-2-BENZOPYRAN-5,6-DIOL HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
CIS-(+/-)-1-(AMINOMETHYL)-3,4-DIHYDRO-3-PHENYL-1H-2-BENZOPYRAN-5,6-DIOL HYDROCHLORIDE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63711 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43348 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-400-6206333 18521732826 | market@aladdin-e.com | China | 25014 | 65 |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8449 | 60 |
| Shanghai Rechem science Co., Ltd. | 21-31433387 15618786686 | sales@rechemscience.com | China | 2985 | 58 |
| BOC Sciences | -- | info@bocsci.com | USA | 0 | 65 |
| MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 | order@med-bio.cn | China | 8141 | 58 |