Methyl 2-(Boc-amino)isonicotinate
- CAS No.
- 639091-75-1
- Chemical Name:
- Methyl 2-(Boc-amino)isonicotinate
- Synonyms
- Methyl 2-(Boc-amino)isonicotinate;2-Boc-amino-isonicotinic acid methyl ester;Methyl 2-((tert-butoxycarbonyl)aMino)isonicotinate;2-tert-Butoxycarbonylamino-isonicotinic acid methyl ester;methyl 2-(tert-butoxycarbonylamino)pyridine-4-carboxylate;Methyl 2-[(2-methylpropan-2-yl)oxycarbonylamino]pyridine-4-carboxylate;2-[[(1,1-Dimethylethoxy)carbonyl]amino]-4-pyridinecarboxylic acidmethylester;4-Pyridinecarboxylic acid, 2-[[(1,1-diMethylethoxy)carbonyl]aMino]-, Methyl ester
- CBNumber:
- CB02499400
- Molecular Formula:
- C12H16N2O4
- Molecular Weight:
- 252.27
- MDL Number:
- MFCD11504796
- MOL File:
- 639091-75-1.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P264-P270-P301+P312-P330 |
| HS Code | 2922390090 |
Methyl 2-(Boc-amino)isonicotinate price More Price(41)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR302224 | Methyl 2-((tert-butoxycarbonyl)amino)isonicotinate 97% | 639091-75-1 | 100mg | $21 | 2026-06-04 | Buy |
| Apolloscientific | OR302224 | Methyl 2-((tert-butoxycarbonyl)amino)isonicotinate 97% | 639091-75-1 | 250mg | $24 | 2026-06-04 | Buy |
| Matrix Scientific | 118101 | Methyl 2-((tert-butoxycarbonyl)amino)isonicotinate | 639091-75-1 | 5.00g | $301 | 2026-05-18 | Buy |
| Matrix Scientific | 018214 | 2-(2,2-Dimethyl-propionylamino)-isonicotinic acidmethyl ester | 639091-75-1 | 500.00mg | $116 | 2026-05-18 | Buy |
| Synthonix | M56036 | Methyl 2-(Boc-amino)isonicotinate 97% | 639091-75-1 | 100mg | $25 | 2026-05-06 | Buy |
Methyl 2-(Boc-amino)isonicotinate Chemical Properties, Uses, Production
Application
2-(BOC-amino)isonicotinic acid methyl ester, also known as Boc-isonicotinic acid methyl ester, is an organic compound widely used in the synthesis of various compounds. It is an important intermediate in the synthesis of pharmaceuticals, agrochemicals, and other chemicals. Furthermore, 2-(BOC-amino)isonicotinic acid methyl ester is used in the synthesis of many other compounds, including amides, nitriles, and amines. It is also used in the synthesis of peptides, peptide analogs, and other peptide mimics.
Synthesis
A 500 mL round bottomed flask was charged with methyl 2-aminoisonicotinate (5.0 g, 32.9 mmol) and suspended in t-BuOH (200 mL). To this stirring solution was added di-tert-butyl dicarbonate (7.53 g, 34.5 mmol). The flask was vented and placed in an oil bath preheated to 50°C. The reaction mixture was let stir overnight. After 22 hours LCMS showed near complete conversion of starting material. The mixture was cooled to room temperature and filtered. The material was taken on without any further purification. Yield 5.93 g of white solid, Methyl 2-(Boc-amino)isonicotinate. 1H NMR (400 MHz, DMSO-d6) δ ppm 10.14 (1H, s), 8.43 (1H, dd, J=5.02, 0.75 Hz), 8.33 (1H, s), 7.45 (1H, dd, J=5.02, 1.51 Hz), 3.89 (3H, s), 1.48 (9H, s).
Methyl 2-(Boc-amino)isonicotinate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Baiyin Chengze Chemical Technology Co., Ltd. | +86 943-8535351 13389336721 | sales@chengzechem.com | China | 300 | 58 |
| Taizhou Tongxin Bio-Tech Co., Ltd | 0523-86818997 18652728585 | sales@allyrise.com | China | 2995 | 60 |
| Nantong MYBio-pharm. Co., Ltd. | 0513-85921823 18662920231 | sales@ntminyanmedical.com | China | 4593 | 58 |
| Shanghai ChuangYan Chemical Technology Co., Ltd. | 021-11111111 11111111111 | 546919421@qq.com | China | 3778 | 55 |
| ShangHai AmK Pharmaceutical Technology Co., Ltd. | 微信 18019252918 18019252918 | sale@amkchem.com | China | 14961 | 55 |
| Shanghai Tombiopharma Chemical Co. Ltd. | 13391076197 | tombiopharma@163.com | China | 4986 | 55 |
| Accela ChemBio Inc. | +1(858) 699-3322 | marketing@accelachem.com | United States | 6022 | 65 |
| Shanghai Boyners Pharm-Tech Co., Ltd. | 13817873692 | mkt@boynerspharm.com | China | 1707 | 55 |
| JW & Y Pharmlab Co., Ltd. | 021-64340559 | xinyu_shi@jwypharmlab.com.cn | China | 11999 | 58 |
