Tubulin Polymerization Inhibitor II

Tubulin Polymerization Inhibitor II structure

CAS No.: 1151995-69-5

Chemical Name:: Tubulin Polymerization Inhibitor II

Synonyms: Tubulin inhibitor 9;Tubulin Polymerization Inhibitor II;2H-Indol-2-one, 1,3-dihydro-6-methoxy-3-[(3,4,5-trimethoxyphenyl)methylene]-

CBNumber:: CB02501835

Molecular Formula:: C19H19NO5

Molecular Weight:: 341.36

MDL Number:

MOL File:: 1151995-69-5.mol

MSDS File:: SDS

Last updated:2023-04-23 13:52:06

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Tubulin Polymerization Inhibitor II Properties

Boiling point	549.5±50.0 °C(Predicted)
Density	1.241±0.06 g/cm3(Predicted)
storage temp.	+2C to +8C
form	Yellow solid
pka	12.16±0.20(Predicted)

Tubulin Polymerization Inhibitor II price More Price(2)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	654164	Tubulin Polymerization Inhibitor II	1151995-69-5	5mg	$172	2024-03-01	Buy
TRC	T897143	Tubulin Polymerization Inhibitor II	1151995-69-5	5mg	$120	2021-12-16	Buy

Product number	Packaging	Price	Buy
654164	5mg	$172	Buy
T897143	5mg	$120	Buy

Tubulin Polymerization Inhibitor II Chemical Properties,Uses,Production

Uses

Tubulin Polymerization Inhibitor II is a Tubulin inhibitor.

General Description

A cell-permeable, SU5416- (Cat. Nos. 676487 and 676498) derived combretastatin A-4 (Cat. No. 234200) analog that acts as an effective anti-microtubule agent (IC₅₀ = 4.5 μM in inhibiting polymerization of purified porcine brain tubulin) and displays extremely potent anti-proliferative activity towards various cancer cell lines (GI₅₀<10 nM for 46 lines among a 53 NCI panel tested).

Biochem/physiol Actions

Cell permeable: yes

Tubulin Polymerization Inhibitor II Preparation Products And Raw materials

Raw materials

Preparation Products

Tubulin Polymerization Inhibitor II Suppliers

Global( 7)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
VDM Biochemicals	0330-2528181	sales@vdmbio.com	United States	510	64
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51471	80
Jinan ponder chemical co. LTD	0531-0000	thinklifescience@163.com	China	19690	58
Energy Chemical	021-58432009 400-005-6266	marketing1@energy-chemical.com	China	44843	58
Jinan Jiuli Biotechnology Co. , Ltd.	15865264761	486064515@qq.com	China	3223	58

Supplier	Advantage
VDM Biochemicals	64
Sigma-Aldrich	80
Jinan ponder chemical co. LTD	58
Energy Chemical	58
Jinan Jiuli Biotechnology Co. , Ltd.	58

Tubulin Polymerization Inhibitor II 2H-Indol-2-one, 1,3-dihydro-6-methoxy-3-[(3,4,5-trimethoxyphenyl)methylene]- Tubulin inhibitor 9 1151995-69-5 Angiogenesis and Metastasis Growth Factors and Cytokines