ChemicalBook >> CAS DataBase List >>(2S,3R)-(+)-4-DIMETHYLAMINO-1,2-DIPHENYL-3-METHYL-2-BUTANOL

(2S,3R)-(+)-4-DIMETHYLAMINO-1,2-DIPHENYL-3-METHYL-2-BUTANOL

CAS No.
38345-66-3
Chemical Name:
(2S,3R)-(+)-4-DIMETHYLAMINO-1,2-DIPHENYL-3-METHYL-2-BUTANOL
Synonyms
chirald;Oxiphene;D-OXYPHENE;chirald tm;CHIRALD(R);DEXTROOXYPHENE;α-(+)-Oxyphene;Darvon alcohol;Einecs 253-893-6;Mosher'S reagent
CBNumber:
CB0251222
Molecular Formula:
C19H25NO
Molecular Weight:
283.41
MDL Number:
MFCD00066214
MOL File:
38345-66-3.mol
MSDS File:
SDS
Last updated:2023-05-04 15:12:56

(2S,3R)-(+)-4-DIMETHYLAMINO-1,2-DIPHENYL-3-METHYL-2-BUTANOL Properties

Melting point 54-56 °C(lit.)
alpha 21 +8.2° (c = 10 in ethanol)
Boiling point bp0.1 mm 138-139°
Flash point >230 °F
optical activity [α]21/D +8.2°, c = 10 in ethanol
Merck 13,2070
BRN 2384178
FDA UNII 5917USS6PV
EPA Substance Registry System Benzeneethanol, ?-[(1R)-2-(dimethylamino)-1-methylethyl]-?-phenyl-, (?S)- (38345-66-3)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P330-P501
WGK Germany  3

(2S,3R)-(+)-4-DIMETHYLAMINO-1,2-DIPHENYL-3-METHYL-2-BUTANOL price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 227404 Chirald? 99% 38345-66-3 50g $1070 2023-06-20 Buy
Sigma-Aldrich 227404 Chirald? 99% 38345-66-3 10g $431 2022-05-15 Buy
American Custom Chemicals Corporation CCH0007188 (2S,3R)-(+)-4-DIMETHYLAMINO-1,2-DIPHENYL-3-METHYL-2-BUTANOL 95.00% 38345-66-3 5MG $504.8 2021-12-16 Buy
American Custom Chemicals Corporation CCH0007188 (2S,3R)-(+)-4-DIMETHYLAMINO-1,2-DIPHENYL-3-METHYL-2-BUTANOL 95.00% 38345-66-3 10G $1575 2021-12-16 Buy
Product number Packaging Price Buy
227404 50g $1070 Buy
227404 10g $431 Buy
CCH0007188 5MG $504.8 Buy
CCH0007188 10G $1575 Buy

(2S,3R)-(+)-4-DIMETHYLAMINO-1,2-DIPHENYL-3-METHYL-2-BUTANOL Chemical Properties,Uses,Production

Uses

Reducing reagent in organic synthesis.

Purification Methods

Purify the hydrochloride by dissolving 1.5g in 13.5 mL of 5N HCl, heat to boiling and evaporate in a vacuum. Recrystallise the hydrochloride three times from MeOH/EtOAc giving m 189-190o, []D -33.7o (c 1, H2O) {enantiomer has +34.2o}. The hydrochloride in the minimum volume of water is basified with aqueous 5N NaOH and extracted with Et2O. The extract is dried (K2CO3) and evaporated, leaving a residue which is stored in a desiccator over solid KOH as a low melting solid. It can be recovered using these procedures from asymmetric reductions with LAH, and re-used. [Pohland & Sullivan J Am Chem Soc 77 3400 1955, Sullivan et al. J Org Chem 28 2483 1963, Beilstein 13 IV 2221.]

(2S,3R)-(+)-4-DIMETHYLAMINO-1,2-DIPHENYL-3-METHYL-2-BUTANOL Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 31)Suppliers
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View Lastest Price from (2S,3R)-(+)-4-DIMETHYLAMINO-1,2-DIPHENYL-3-METHYL-2-BUTANOL manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(2S,3R)-(+)-4-DIMETHYLAMINO-1,2-DIPHENYL-3-METHYL-2-BUTANOL pictures 2019-07-06 (2S,3R)-(+)-4-DIMETHYLAMINO-1,2-DIPHENYL-3-METHYL-2-BUTANOL
38345-66-3
US $1.00 / kg 1kg 95%-99% 10kg Career Henan Chemical Co
2-S-3-R-plus-4-dimethylamino-1-2-*diphenyl-3-meth chirald [S-(R*,S*)]-alpha-[2-(dimethylamino)-1-methylethyl]-alpha-phenylphenethyl alcohol DEXTROOXYPHENE chirald tm D-OXYPHENE (2S,3R)-4-(DIMETHYLAMINO)-3-METHYL-1,2-DIPHENYLBUTAN-2-OL, TOLUENE SOLUTION Dextrocarbinol base, (2S,3R)-(+)-4-Dimethylamino-1,2-diphenyl-3-methyl-2-butanol, (2S,3R)-(+)-4-Dimethylamino-3-methyl-1,2-diphenyl-2-butanol Dextrocarbinol base, (2S,3R)-(+)-4-Dimethylamino-1,2-diphenyl-3-methyl-2-butanol (2S,3R)-1,2-Diphenyl-3-methyl-4-(dimethylamino)-2-butanol (αS)-α-[(1R)-2-(Dimethylamino)-1-methylethyl]-α-phenylbenzeneethanol (αS)-α-Phenyl-α-[(R)-1-(dimethylaminomethyl)ethyl]benzeneethanol α-(+)-Oxyphene Darvon alcohol Einecs 253-893-6 Mosher'S reagent Oxiphene (2S,3R)-(+)-4-DIMETHYLAMINO-1,2-DIPHENYL-3-METHYL-2-BUTANOL (2S,3R)-4-DIMETHYLAMINO-1,2-DIPHENYL-3-METHYL-2-BUTANOL (+)-(2S,3R)-4-DIMETHYLAMINO-3-METHYL-1,2-DIPHENYL-2-BUTANOL DEXTROCARBINOL BASE CHIRALD(R) (2S,3R)-4-(dimethylamino)-3-methyl-1,2-diphenylbutan-2-ol (2S,3R)-(+)-4-Dimethylamino-1,2-diphenyl-3-methyl-2-butanol, (2S,3R)-(+)-4-Dimethylamino-3-methyl-1,2-diphenyl-2-butanol, Dextrocarbinol base (2S,3R)-4-(Dimethylamino)-1,2-diphe Benzeneethanol, α-[(1R)-2-(dimethylamino)-1-methylethyl]-α-phenyl-, (αS)- Dextropropoxyphene EP Impurity A Propoxyphene USP Related Compound A (2S,3R)-4-(dimethylamino)-1,2-diphenyl-3-methyl-butan-2-ol (oxyphene), Dextropropoxyphene Hydrochloride EP Impurity A Codeine Phosphate Impurity 14 38345-66-3 Organic Building Blocks Chiral Building Blocks Asymmetric Synthesis Amino Alcohols