ChemicalBook >> CAS DataBase List >>FX-11
FX-11
- CAS No.
- 213971-34-7
- Chemical Name:
- FX-11
- Synonyms
- DK664;FX-11;FX11,FX 11;LDHA Inhibitor FX11;FX-11 (LDHA inhibitor FX11);7-Benzyl-2,3-dihydroxy-6-methyl-4-propyl-1-naphthoic acid;7-benzyl-2,3-dihydroxy-6-methyl-4-propylnaphthalene-1-carboxylic acid;2,3-Dihydroxy-6-Methyl-7-(phenylMethyl)-4-propyl-1-naphthalenecarboxylic Acid;1-Naphthalenecarboxylic acid, 2,3-dihydroxy-6-methyl-7-(phenylmethyl)-4-propyl-
- CBNumber:
- CB02627892
- Molecular Formula:
- C22H22O4
- Molecular Weight:
- 350.41
- MDL Number:
- MOL File:
- 213971-34-7.mol
- MSDS File:
- SDS
Last updated:2024-08-13 09:54:52
| Melting point | 183-184 °C |
|---|---|
| Boiling point | 570.1±50.0 °C(Predicted) |
| Density | 1.260±0.06 g/cm3(Predicted) |
| storage temp. | -20°C Freezer, Under inert atmosphere |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 3.70±0.40(Predicted) |
| color | Light Grey to Light Brown |
| InChI | InChI=1S/C22H22O4/c1-3-7-16-17-10-13(2)15(11-14-8-5-4-6-9-14)12-18(17)19(22(25)26)21(24)20(16)23/h4-6,8-10,12,23-24H,3,7,11H2,1-2H3,(H,25,26) |
| InChIKey | LVPYVYFMCKYFCZ-UHFFFAOYSA-N |
| SMILES | C1(C(O)=O)=C2C(C=C(C)C(CC3=CC=CC=C3)=C2)=C(CCC)C(O)=C1O |
FX-11 price More Price(12)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 427218 | Lactate Dehydrogenase A Inhibitor, FX11 - Calbiochem | 213971-34-7 | 10mg | $259 | 2024-03-01 | Buy |
| TRC | D453265 | 2,3-Dihydroxy-6-methyl-7-(phenylmethyl)-4-propyl-1-naphthalenecarboxylicAcid | 213971-34-7 | 0.5mg | $200 | 2021-12-16 | Buy |
| ChemScene | CS-0006190 | FX-11 98.11% | 213971-34-7 | 5mg | $120 | 2021-12-16 | Buy |
| ChemScene | CS-0006190 | FX-11 98.11% | 213971-34-7 | 10mg | $190 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FD164039 | 2,3-Dihydroxy-6-methyl-7-(phenylmethyl)-4-propyl-1-naphthalenecarboxylic Acid | 213971-34-7 | 500ug | $500 | 2021-12-16 | Buy |
FX-11 Chemical Properties,Uses,Production
Description
FX-11 is an inhibitor of lactate dehydrogenase-A (LDH-A; Ki = 8 μM). It is selective for LDH-A over GAPDH (Ki = >300 μM). FX-11 increases oxygen consumption and the production of reactive oxygen species (ROS), as well as induces cell death in P493-6 lymphoblastoid cells. In vivo, FX-11 (42 μg/animal, i.p.) reduces tumor volume in a P493-6 mouse xenograft model. It also reduces tumor weight in a BxPC-3 mouse xenograft model when administered at a dose of 2 mg/kg.
Uses
This compound is used in the synthesis of novel lactate dehydrogenase A inhibitors.This compound is suitable for lactate dehydrogenase (LDH) related research.
FX-11 Preparation Products And Raw materials
Raw materials
Preparation Products
FX-11 Suppliers
Global( 45)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Zhuangming Biopharma Co., Ltd. | +86-19189228086 +86-18858568638 | sales@zmsilane.com | China | 629 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8617531190177 | peter@yan-xi.com | China | 5873 | 58 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 18628 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49739 | 58 |
| Nantong HI-FUTURE Biology Co., Ltd. | +undefined18051384581 | sales@chemhifuture.com | China | 3136 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +undefined18621343501 | product@acmec-e.com | China | 33350 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| Junwee Chemical co., Ltd. | +86-571-85808636 +86-13958122542 | sales@junweechem.com | China | 821 | 58 |
View Lastest Price from FX-11 manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-08-15 | 7-Benzyl-2,3-dihydroxy-6-methyl-4-propyl-1-naphthoic acid
213971-34-7
|
US $50.00 / kg | 1kg | 0.99 | 20 tons | Hebei Yanxi Chemical Co., Ltd. |
-
- 7-Benzyl-2,3-dihydroxy-6-methyl-4-propyl-1-naphthoic acid
213971-34-7
- US $50.00 / kg
- 0.99
- Hebei Yanxi Chemical Co., Ltd.
FX-11
2,3-Dihydroxy-6-Methyl-7-(phenylMethyl)-4-propyl-1-naphthalenecarboxylic Acid
7-benzyl-2,3-dihydroxy-6-methyl-4-propylnaphthalene-1-carboxylic acid
FX-11
(LDHA inhibitor FX11)
LDHA Inhibitor FX11
1-Naphthalenecarboxylic acid, 2,3-dihydroxy-6-methyl-7-(phenylmethyl)-4-propyl-
DK664
FX11,FX 11
7-Benzyl-2,3-dihydroxy-6-methyl-4-propyl-1-naphthoic acid
213971-34-7
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