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Kibdelone C

CAS No.
934464-79-6
Chemical Name:
Kibdelone C
Synonyms
Kibdelone C;2H-[1]Benzopyrano[2',3':6,7]naphth[2,1-g]isoquinoline-1,14-dione, 4-chloro-6,7,10,11,12,13-hexahydro-5,10,12,13,15,16-hexahydroxy-8-methoxy-2-methyl-3-propyl-, (10S,12S,13R)-
CBNumber:
CB02703741
Molecular Formula:
C29H28ClNO10
Molecular Weight:
585.99
MDL Number:
MOL File:
934464-79-6.mol
MSDS File:
SDS
Last updated:2023-05-21 10:59:17

Kibdelone C Properties

Melting point 265-267 °C(Solv: benzene (71-43-2))
Boiling point 968.8±65.0 °C(Predicted)
Density 1.71±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF: Soluble; DMSO: Soluble; Ethanol: Soluble; Methanol: Soluble
form A solid
pka 6.44±0.70(Predicted)

Kibdelone C price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 21525 Kibdelone C ≥95% 934464-79-6 1mg $285 2024-03-01 Buy
TRC K570518 KibdeloneC 934464-79-6 2.5mg $475 2021-12-16 Buy
Product number Packaging Price Buy
21525 1mg $285 Buy
K570518 2.5mg $475 Buy

Kibdelone C Chemical Properties,Uses,Production

Description

Kibdelone C is a member of a family of natural heterocyclic polyketides first isolated from a soil actinomycete, Kibdelosporangium. Kibdelones have been described as having potent and selective cytotoxicity against a panel of human tumor cell lines, and kibdelone C has low nanomolar effectiveness in these assays. Kibdelone C disrupts the actin cytoskeleton without directly binding actin or affecting its polymerization in vitro.

Uses

Kibdelone C is the major analogue of a potent antitumor complex.

Uses

Kibdelone C is the major analogue of a potent antitumor complex isolated from Kibdelosporangium sp.. Structurally, kibdelone C is related to lysolipin and albofungin, however no comparative investigation of this class has been reported. The mode of action and pharmacology of the kibdelones has received little attention.

Uses

Kibdelone C is the major analogue of a potent antitumour complex isolated from Kibdelosporangium sp.. Structurally, kibdelone C is related to lysolipin and albofungin, however no comparative investigation of this class has been reported. The mode of action and pharmacology of the kibdelones has received little attention.

Kibdelone C Preparation Products And Raw materials

Raw materials

Preparation Products

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Kibdelone C 2H-[1]Benzopyrano[2',3':6,7]naphth[2,1-g]isoquinoline-1,14-dione, 4-chloro-6,7,10,11,12,13-hexahydro-5,10,12,13,15,16-hexahydroxy-8-methoxy-2-methyl-3-propyl-, (10S,12S,13R)- 934464-79-6